Hyaluronic Acid
274 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
274
Total Reports
8
Deaths Reported
290.0%
Death Rate
Active Ingredients
Hyaluronic Acid
Administration Routes
UnknownIntra-ArticularOphthalmicOralParenteralIntraocular
Species Affected
Unknown 140
Dog 86
Horse 35
Cat 9
Human 2
Guinea Pig 1
Other 1
Most Affected Breeds
Unknown 144
Quarter Horse 14
Crossbred Canine/dog 12
Shih Tzu 9
Chihuahua 7
Retriever - Labrador 5
Crossbred Equine/horse 5
Domestic Shorthair 5
Warmblood (unspecified) 5
Pug 5
Most Reported Reactions
Corneal ulcer 19
Ocular discharge 17
Underfilling, Bottles 16
Solution, Abnormal 15
Diarrhoea 13
Dispenser, Abnormal 13
Eye pain 13
Lethargy (see also Central nervous system depression in 'Neurological') 13
Other abnormal test result NOS 13
Behavioural disorder NOS 13
Applicator, Abnormal 13
Underfilling, Package 12
Outcome Breakdown
Recovered/Normal
55 (40.7%)
Outcome Unknown
54 (40.0%)
Ongoing
13 (9.6%)
Recovered with Sequela
5 (3.7%)
Euthanized
4 (3.0%)
Died
4 (3.0%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.