Florfenicol/Flunixin Inj-Triac

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268 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
268
Total Reports
137
Deaths Reported
5110.0%
Death Rate

Active Ingredients

Florfenicol/Flunixin Inj-Triac

Administration Routes

SubcutaneousUnknownIntramuscularParenteralOtherTopicalOral

Species Affected

Cattle 172
Unknown 63
Human 23
Goat 5
Sheep 4
Pig 1

Most Affected Breeds

Unknown 87
Cattle (other) 68
Crossbred Bovine/Cattle 25
Aberdeen Angus 19
Holstein-Friesian also known as Holstein 18
Cattle (unspecified) 7
Jersey 7
Red Angus 5
Mixed (Cattle) 4
Cattle (unknown) 4

Most Reported Reactions

Death 126
Lack of efficacy - NOS 90
Lack of efficacy (bacteria) - NOS 35
Containers, Damaged 19
Appearance, Abnormal 18
Injection site pain 13
Respiratory signs 12
Injection site swelling 8
Containers, Leaking 8
Necropsy performed 8
CULTURE/TITER DATA ABNORMAL 7
Defect Unknown/Not Specified 7

Outcome Breakdown

Died
132 (43.7%)
Ongoing
78 (25.8%)
Outcome Unknown
43 (14.2%)
Recovered/Normal
43 (14.2%)
Euthanized
5 (1.7%)
Recovered with Sequela
1 (0.3%)

Data Summary

Metric Value
Total adverse event reports 268
Reports involving death 137
Case-fatality rate (reported events) 5110.0%
Distinct species in reports 6
Distinct breeds in reports 20
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Florfenicol/Flunixin Inj-Triac Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 268 adverse event reports referencing Florfenicol/Flunixin Inj-Triac, including 137 reports in which the animal died — a 5110.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Florfenicol/Flunixin Inj-Triac. Reported administration routes include Subcutaneous, Unknown, Intramuscular, Parenteral. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Florfenicol/Flunixin Inj-Triac reports are Cattle (172 reports), Unknown (63 reports), Human (23 reports), with Cattle accounting for the largest share. Within those species, Unknown (87), Cattle (other) (68), Crossbred Bovine/Cattle (25) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Florfenicol/Flunixin Inj-Triac are Death (126), Lack of efficacy - NOS (90), Lack of efficacy (bacteria) - NOS (35), Containers, Damaged (19). Of the 302 reports with a coded outcome, Died is the leading category at 43.7%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Florfenicol/Flunixin Inj-Triac.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial