Thyroid Medication

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105 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
105
Total Reports
18
Deaths Reported
1710.0%
Death Rate

Active Ingredients

Thyroid Medication

Administration Routes

OralUnknownTopicalSubcutaneous

Species Affected

Dog 95
Cat 7
Human 3

Most Affected Breeds

Retriever - Labrador 18
Shepherd Dog - German 10
Beagle 6
Domestic Shorthair 5
Shih Tzu 4
Boxer (German Boxer) 4
Retriever - Golden 4
Dog (unknown) 4
Unknown 3
Chihuahua 3

Most Reported Reactions

Diarrhoea 15
Vomiting 15
Death by euthanasia 11
Decreased appetite 10
Seizure NOS 9
Polydipsia 8
Lethargy (see also Central nervous system depression in 'Neurological') 8
Ataxia 7
Weight loss 7
Polyuria 7
Lack of efficacy - NOS 6
Death 6

Outcome Breakdown

Outcome Unknown
33 (31.4%)
Ongoing
32 (30.5%)
Recovered/Normal
20 (19.0%)
Euthanized
11 (10.5%)
Died
7 (6.7%)
Recovered with Sequela
2 (1.9%)

Data Summary

Metric Value
Total adverse event reports 105
Reports involving death 18
Case-fatality rate (reported events) 1710.0%
Distinct species in reports 3
Distinct breeds in reports 20
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Thyroid Medication Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 105 adverse event reports referencing Thyroid Medication, including 18 reports in which the animal died — a 1710.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Thyroid Medication. Reported administration routes include Oral, Unknown, Topical, Subcutaneous. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Thyroid Medication reports are Dog (95 reports), Cat (7 reports), Human (3 reports), with Dog accounting for the largest share. Within those species, Retriever - Labrador (18), Shepherd Dog - German (10), Beagle (6) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Thyroid Medication are Diarrhoea (15), Vomiting (15), Death by euthanasia (11), Decreased appetite (10). Of the 105 reports with a coded outcome, Outcome Unknown is the leading category at 31.4%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Thyroid Medication.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial