Lactated Ringers

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79 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
79
Total Reports
23
Deaths Reported
2910.0%
Death Rate

Active Ingredients

Lactated Ringers

Administration Routes

IntravenousSubcutaneousUnknownParenteralOral

Species Affected

Dog 60
Cat 18
Rabbit 1

Most Affected Breeds

Crossbred Canine/dog 15
Domestic Shorthair 12
Unknown 5
Terrier - Yorkshire 5
Retriever - Golden 3
Shih Tzu 3
Dog (unknown) 2
Collie - Smooth-haired 2
Siamese 2
Poodle - Standard 2

Most Reported Reactions

Vomiting 15
Dehydration 13
Death by euthanasia 12
Diarrhoea 10
Lethargy (see also Central nervous system depression in Neurological) 10
Weight loss 9
Decreased appetite 9
Elevated alanine aminotransferase (ALT) 9
Lack of efficacy - NOS 9
Seizure NOS 8
Hypernatremia 8
Elevated total bilirubin 8

Outcome Breakdown

Ongoing
25 (31.3%)
Recovered/Normal
23 (28.7%)
Euthanized
12 (15.0%)
Died
11 (13.8%)
Outcome Unknown
8 (10.0%)
Recovered with Sequela
1 (1.3%)

Data Summary

Metric Value
Total adverse event reports 79
Reports involving death 23
Case-fatality rate (reported events) 2910.0%
Distinct species in reports 3
Distinct breeds in reports 20
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Lactated Ringers Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 79 adverse event reports referencing Lactated Ringers, including 23 reports in which the animal died — a 2910.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Lactated Ringers. Reported administration routes include Intravenous, Subcutaneous, Unknown, Parenteral. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Lactated Ringers reports are Dog (60 reports), Cat (18 reports), Rabbit (1 reports), with Dog accounting for the largest share. Within those species, Crossbred Canine/dog (15), Domestic Shorthair (12), Unknown (5) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Lactated Ringers are Vomiting (15), Dehydration (13), Death by euthanasia (12), Diarrhoea (10). Of the 80 reports with a coded outcome, Ongoing is the leading category at 31.3%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Lactated Ringers.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial