Drug profile

The FDA adverse-event record for Lactated Ringers

87 FDA reports name Lactated Ringers, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#840 of 2,679
by report volume (all drugs)
87
adverse-event reports
27.6%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Lactated Ringers ranks #834 of 2679 by total reports (87) and #145 of 1130 by death-coded share (27.6%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#834
This drug, reports of 2679
#145
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Lactated Ringers has 87 reports now versus 83 in that prior snapshot: 4 more (4.8%).

Report change
+4
Death-coded reports
+1
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Lactated Ringers changes

Signature read: Lactated Ringers's 27.6% death-coded share is among the highest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
87
Total Reports
24
Deaths Reported
27.6%
Death-coded share of reports

Active Ingredients

Lactated Ringers

Administration Routes

IntravenousSubcutaneousUnknownParenteralOral

Species Affected

Dog 64
Cat 22
Rabbit 1

Most Affected Breeds

Crossbred Canine/dog 15
Domestic Shorthair 14
Unknown 5
Terrier - Yorkshire 5
Shih Tzu 4
Retriever - Golden 3
Dog (unknown) 2
Shepherd Dog - Australian 2
Collie - Smooth-haired 2
Siamese 2

Most Reported Reactions

Vomiting 18
Lethargy (see also Central nervous system depression in Neurological) 15
Dehydration 14
Lack of efficacy - NOS 14
Death by euthanasia 12
Diarrhoea 11
Weight loss 10
Decreased appetite 10
Elevated alanine aminotransferase (ALT) 9
Elevated total bilirubin 9
Seizure NOS 8
Hypernatremia 8

Outcome Breakdown

Ongoing
29 (33.0%)
Recovered/Normal
26 (29.5%)
Died
12 (13.6%)
Euthanized
12 (13.6%)
Outcome Unknown
8 (9.1%)
Recovered with Sequela
1 (1.1%)

Lactated Ringers: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Lactated Ringers, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Lactated Ringers (#840 of 2,679 by report volume); death-coded 27.6%. PlainBreed drug row · death-coded share stamp 27.6% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →