Progesterone; Estradiol Benzoate
54 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
54
Total Reports
15
Deaths Reported
2780.0%
Death Rate
Active Ingredients
Progesterone; Estradiol Benzoate
Administration Routes
UnknownSubcutaneous
Species Affected
Cattle 32
Unknown 21
Human 1
Most Affected Breeds
Unknown 22
Cattle (other) 10
Mixed (Cattle) 9
Holstein-Friesian also known as Holstein 6
Aberdeen Angus 5
Cattle (unknown) 1
Hereford cattle 1
Most Reported Reactions
Death 11
No sign 7
Increased sexual interest 7
Lack of efficacy (bacteria) - NOS 6
Implant, Abnormal 6
Containers, Damaged 5
Uncoded sign 4
Underfilling, Package 4
Lack of efficacy - NOS 3
Anaphylactic-type reaction 3
Sexual disorder NOS (see 'Reproductive' for named sexual disorders) 3
Joint swelling 2
Outcome Breakdown
Outcome Unknown
16 (36.4%)
Died
15 (34.1%)
Recovered/Normal
7 (15.9%)
Recovered with Sequela
3 (6.8%)
Ongoing
2 (4.5%)
Euthanized
1 (2.3%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.