Ivermectin 68Mcg, Pyrantel Pamoate 57Mg, Praziquantel 57Mg

1,322 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
1,322
Total Reports
16
Deaths Reported
120.0%
Death Rate

Active Ingredients

Ivermectin 68Mcg, Pyrantel Pamoate 57Mg, Praziquantel 57Mg

Administration Routes

OralUnknown

Species Affected

Dog 1,246
Unknown 71
Human 4
Cat 1

Most Affected Breeds

Shih Tzu 134
Dachshund (unspecified) 87
Crossbred Canine/dog 82
Unknown 75
Chihuahua 64
Terrier - Yorkshire 62
Terrier - Jack Russell 58
Poodle - Toy 51
Maltese 40
Mixed (Dog) 40

Most Reported Reactions

Vomiting 771
Lethargy (see also Central nervous system depression in 'Neurological') 210
Diarrhoea 160
INEFFECTIVE, HEARTWORM LARVAE 126
Lack of efficacy - NOS 109
Lack of efficacy (endoparasite) - hookworm 89
INEFFECTIVE, ASCARIDS NOS 55
Uncoded sign 45
Underfilling, Package 40
Behavioural disorder NOS 38
Shaking 35
Overdose 35

Outcome Breakdown

Recovered/Normal
805 (64.3%)
Outcome Unknown
410 (32.7%)
Died
12 (1.0%)
Recovered with Sequela
11 (0.9%)
Ongoing
10 (0.8%)
Euthanized
4 (0.3%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.