Flea And Tick Shampoo

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156 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
156
Total Reports
2
Deaths Reported
130.0%
Death Rate

Active Ingredients

Flea And Tick Shampoo

Administration Routes

TopicalCutaneousUnknownOther

Species Affected

Dog 134
Cat 22

Most Affected Breeds

Chihuahua 18
Crossbred Canine/dog 13
Dog (unknown) 13
Domestic Shorthair 13
Retriever - Labrador 8
Shih Tzu 5
Poodle (unspecified) 5
Shepherd Dog - German 5
Maltese 5
Dachshund (unspecified) 4

Most Reported Reactions

Lack of efficacy (ectoparasite) - flea 92
Lack of efficacy (flea) 30
Product label issues 16
Pruritus 10
Vocalisation 9
Overdose 9
Itching 8
Lack of efficacy - NOS 7
Lethargy (see also Central nervous system depression in 'Neurological') 7
Behavioural disorder NOS 6
Scratching 5
Lack of efficacy (ectoparasite) - tick NOS 4

Outcome Breakdown

Outcome Unknown
127 (81.4%)
Ongoing
14 (9.0%)
Recovered/Normal
13 (8.3%)
Died
1 (0.6%)
Euthanized
1 (0.6%)

Data Summary

Metric Value
Total adverse event reports 156
Reports involving death 2
Case-fatality rate (reported events) 130.0%
Distinct species in reports 2
Distinct breeds in reports 20
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Flea And Tick Shampoo Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 156 adverse event reports referencing Flea And Tick Shampoo, including 2 reports in which the animal died — a 130.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Flea And Tick Shampoo. Reported administration routes include Topical, Cutaneous, Unknown, Other. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Flea And Tick Shampoo reports are Dog (134 reports), Cat (22 reports), with Dog accounting for the largest share. Within those species, Chihuahua (18), Crossbred Canine/dog (13), Dog (unknown) (13) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Flea And Tick Shampoo are Lack of efficacy (ectoparasite) - flea (92), Lack of efficacy (flea) (30), Product label issues (16), Pruritus (10). Of the 156 reports with a coded outcome, Outcome Unknown is the leading category at 81.4%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Flea And Tick Shampoo.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial