Drug profile

The FDA adverse-event record for Fluid Therapy (Unknown)

422 FDA reports name Fluid Therapy (Unknown), a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#343 of 2,679
by report volume (all drugs)
422
adverse-event reports
22.0%
death-coded share
Cat
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Fluid Therapy (Unknown) ranks #343 of 2679 by total reports (422) and #205 of 1130 by death-coded share (22.0%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#343
This drug, reports of 2679
#205
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Fluid Therapy (Unknown) has 422 reports now versus 411 in that prior snapshot: 11 more (2.7%).

Report change
+11
Death-coded reports
+3
Death-coded share
+0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Fluid Therapy (Unknown) changes

Signature read: death-coded report count at 93 is the most distinctive stamp on Fluid Therapy (Unknown)'s FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
422
Total Reports
93
Deaths Reported
22.0%
Death-coded share of reports

Active Ingredients

Fluid Therapy (Unknown)

Administration Routes

SubcutaneousUnknownIntravenousParenteralOther

Species Affected

Cat 252
Dog 170

Most Affected Breeds

Domestic Shorthair 143
Domestic Longhair 28
Retriever - Labrador 28
Cat (unknown) 28
Domestic Mediumhair 18
Pit Bull 10
Siamese 8
Poodle - Miniature 8
Maine Coon 6
Maltese 6

Most Reported Reactions

Not eating 93
Vomiting 78
Lethargy (see also Central nervous system depression in Neurological) 75
Death by euthanasia 68
Behavioural disorder NOS 68
Other abnormal test result NOS 59
Dehydration 51
Diarrhoea 51
Weight loss 49
Elevated blood urea nitrogen (BUN) 40
Decreased appetite 39
Hyperglycaemia 37

Outcome Breakdown

Ongoing
147 (34.8%)
Outcome Unknown
114 (27.0%)
Recovered/Normal
67 (15.8%)
Euthanized
67 (15.8%)
Died
26 (6.1%)
Recovered with Sequela
2 (0.5%)

Fluid Therapy (Unknown): high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Fluid Therapy (Unknown), both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

  • Compare Fluid Therapy (Unknown)'s report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Fluid Therapy (Unknown) (#343 of 2,679 by report volume); death-coded 22.0%. PlainBreed drug row · death-coded report count stamp 93 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →