Drug profile

The FDA adverse-event record for Fluid Therapy

964 FDA reports name Fluid Therapy, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#188 of 2,679
by report volume (all drugs)
964
adverse-event reports
29.0%
death-coded share
Cat
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Fluid Therapy ranks #187 of 2679 by total reports (964) and #128 of 1130 by death-coded share (29.0%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#187
This drug, reports of 2679
#128
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Fluid Therapy has 964 reports now versus 900 in that prior snapshot: 64 more (7.1%).

Report change
+64
Death-coded reports
+14
Death-coded share
−0.5 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Fluid Therapy changes

Signature read: death-coded report count at 280 is the most distinctive stamp on Fluid Therapy's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
964
Total Reports
280
Deaths Reported
29.0%
Death-coded share of reports

Active Ingredients

Fluid Therapy

Administration Routes

SubcutaneousIntravenousUnknownParenteralOtherAuricular (Otic)

Species Affected

Cat 584
Dog 376
Cattle 1
Horse 1
Fallow 1
Other Birds 1

Most Affected Breeds

Domestic Shorthair 357
Domestic Longhair 53
Cat (unknown) 46
Domestic Mediumhair 44
Retriever - Labrador 40
Retriever - Golden 16
Ragdoll 15
Shepherd Dog - Australian 15
Chihuahua 14
Shih Tzu 13

Most Reported Reactions

Lethargy (see also Central nervous system depression in Neurological) 245
Not eating 234
Vomiting 188
Death by euthanasia 154
Diarrhoea 148
Behavioural disorder NOS 142
Other abnormal test result NOS 130
Death 117
Dehydration 117
Weight loss 103
Anorexia 101
Elevated alanine aminotransferase (ALT) 95

Outcome Breakdown

Ongoing
325 (33.3%)
Outcome Unknown
225 (23.1%)
Euthanized
150 (15.4%)
Recovered/Normal
142 (14.6%)
Died
133 (13.6%)

Fluid Therapy: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Fluid Therapy, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar death-coded share

Nearest other drugs by death-coded share (29.0% here), distinct from the volume row.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Fluid Therapy (#188 of 2,679 by report volume); death-coded 29.0%. PlainBreed drug row · death-coded report count stamp 280 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →