Drug profile

The FDA adverse-event record for Fluid Therapy

779 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Fluid Therapy. See the species affected, top reactions, and outcomes below.

779
adverse-event reports
30.8%
death-coded share
Cat
most-reported species
184
Not eating - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
779
Total Reports
240
Deaths Reported
30.8%
Death Rate

Active Ingredients

Fluid Therapy

Administration Routes

IntravenousSubcutaneousUnknownParenteralOtherAuricular (Otic)

Species Affected

Cat 473
Dog 303
Cattle 1
Horse 1
Fallow 1

Most Affected Breeds

Domestic Shorthair 291
Domestic Longhair 42
Cat (unknown) 40
Domestic Mediumhair 32
Retriever - Labrador 31
Retriever - Golden 14
Ragdoll 12
Dog (unknown) 12
Shih Tzu 12
Chihuahua 12

Most Reported Reactions

Not eating 184
Lethargy (see also Central nervous system depression in Neurological) 172
Vomiting 144
Death by euthanasia 132
Behavioural disorder NOS 115
Diarrhoea 111
Other abnormal test result NOS 103
Death 99
Dehydration 86
Weight loss 84
Anorexia 78
Lack of efficacy - NOS 68

Outcome Breakdown

Ongoing
244 (30.9%)
Outcome Unknown
184 (23.3%)
Euthanized
128 (16.2%)
Recovered/Normal
119 (15.1%)
Died
115 (14.6%)

Fluid Therapy Adverse Event Insights

779 reports name Fluid Therapy; 240 recorded a death outcome (30.8% of reported events, not a population-level mortality rate). Active ingredient: Fluid Therapy. Administration routes: Intravenous, Subcutaneous, Unknown, Parenteral.

By species: Cat (473 reports), Dog (303 reports), Cattle (1 reports). By breed: Domestic Shorthair (291), Domestic Longhair (42), Cat (unknown) (40).

Leading clinical signs: Not eating (184), Lethargy (see also Central nervous system depression in Neurological) (172), Vomiting (144), Death by euthanasia (132). Outcome, 790 coded reports: Ongoing leads at 30.9%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.