Drug profile

The FDA adverse-event record for Dexamethasone Sodium Phosphate

810 FDA reports name Dexamethasone Sodium Phosphate, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#215 of 2,679
by report volume (all drugs)
810
adverse-event reports
29.3%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Dexamethasone Sodium Phosphate ranks #215 of 2679 by total reports (810) and #127 of 1130 by death-coded share (29.3%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#215
This drug, reports of 2679
#127
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Dexamethasone Sodium Phosphate has 810 reports now versus 775 in that prior snapshot: 35 more (4.5%).

Report change
+35
Death-coded reports
+6
Death-coded share
−0.5 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Dexamethasone Sodium Phosphate changes

Signature read: death-coded report count at 237 is the most distinctive stamp on Dexamethasone Sodium Phosphate's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
810
Total Reports
237
Deaths Reported
29.3%
Death-coded share of reports

Active Ingredients

Dexamethasone Sodium Phosphate

Administration Routes

UnknownIntravenousSubcutaneousParenteralIntramuscularAuricular (Otic)OtherOralTopical

Species Affected

Dog 619
Cat 164
Unknown 23
Ferret 2
Horse 1
Lynx 1

Most Affected Breeds

Domestic Shorthair 102
Retriever - Labrador 53
Terrier - Bull - American Pit 34
Unknown 28
Shih Tzu 28
Bulldog - French 26
Chihuahua 25
Retriever - Golden 25
Shepherd Dog - German 20
Crossbred Canine/dog 20

Most Reported Reactions

Vomiting 236
Lethargy (see also Central nervous system depression in 'Neurological') 149
Anaphylaxis 130
Death by euthanasia 124
Death 112
Other abnormal test result NOS 105
Diarrhoea 105
Lethargy (see also Central nervous system depression in Neurological) 102
Pale mucous membrane 93
Not eating 90
Fever 85
Anorexia 81

Outcome Breakdown

Ongoing
311 (39.5%)
Recovered/Normal
136 (17.3%)
Euthanized
122 (15.5%)
Died
116 (14.7%)
Outcome Unknown
97 (12.3%)
Recovered with Sequela
6 (0.8%)

Dexamethasone Sodium Phosphate: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Dexamethasone Sodium Phosphate, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar death-coded share

Nearest other drugs by death-coded share (29.3% here), distinct from the volume row.

What to do with this drug

  • Compare Dexamethasone Sodium Phosphate's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Dexamethasone Sodium Phosphate (#215 of 2,679 by report volume); death-coded 29.3%. PlainBreed drug row · death-coded report count stamp 237 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →