Drug profile

The FDA adverse-event record for Flea Spray (Unknown)

93 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Flea Spray (Unknown). See the species affected, top reactions, and outcomes below.

93
adverse-event reports
1.1%
death-coded share
Dog
most-reported species
52
Lack of efficacy (ectoparasite) - flea - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
93
Total Reports
1
Deaths Reported
1.1%
Death Rate

Active Ingredients

Flea Spray (Unknown)

Administration Routes

OtherTopicalUnknownCutaneous

Species Affected

Dog 68
Cat 25

Most Affected Breeds

Domestic Shorthair 11
Dog (unknown) 6
Terrier - Jack Russell 5
Dachshund - Miniature 5
Cat (unknown) 5
Retriever - Labrador 4
Chihuahua 4
Maine Coon 4
Crossbred Canine/dog 4
Terrier - Yorkshire 3

Most Reported Reactions

Lack of efficacy (ectoparasite) - flea 52
Lack of efficacy (flea) 22
Product label issues 7
Vomiting 6
Lethargy (see also Central nervous system depression in 'Neurological') 6
Drug dose administration interval too short 5
Lot # and/or Expiration date illegible 5
Behavioural disorder NOS 4
Overdose 4
Scratching 3
Panting 3
Walking difficulty 3

Outcome Breakdown

Outcome Unknown
64 (68.8%)
Ongoing
22 (23.7%)
Recovered/Normal
6 (6.5%)
Died
1 (1.1%)

Flea Spray (Unknown) Adverse Event Insights

93 reports name Flea Spray (Unknown); 1 recorded a death outcome (1.1% of reported events, not a population-level mortality rate). Active ingredient: Flea Spray (Unknown). Administration routes: Other, Topical, Unknown, Cutaneous.

By species: Dog (68 reports), Cat (25 reports). By breed: Domestic Shorthair (11), Dog (unknown) (6), Terrier - Jack Russell (5).

Leading clinical signs: Lack of efficacy (ectoparasite) - flea (52), Lack of efficacy (flea) (22), Product label issues (7), Vomiting (6). Outcome, 93 coded reports: Outcome Unknown leads at 68.8%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.