Drug profile

The FDA adverse-event record for Feline Calicivirus,F-9,Live + Feline Panleukopenia Virus,Johnson Leopard Origin,Live + Feline Rhinotracheitis Virus,F2,Live

95 FDA reports name Feline Calicivirus,F-9,Live + Feline Panleukopenia Virus,Johnson Leopard Origin,Live + Feline Rhinotracheitis Virus,F2,Live, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#798 of 2,679
by report volume (all drugs)
95
adverse-event reports
15.8%
death-coded share
Cat
most-reported species
Verify with FDA CVM →

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Feline Calicivirus,F-9,Live + Feline Panleukopenia Virus,Johnson Leopard Origin,Live + Feline Rhinotracheitis Virus,F2,Live ranks #797 of 2679 by total reports (95) and #341 of 1130 by death-coded share (15.8%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#797
This drug, reports of 2679
#341
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Feline Calicivirus,F-9,Live + Feline Panleukopenia Virus,Johnson Leopard Origin,Live + Feline Rhinotracheitis Virus,F2,Live has 95 reports now versus 94 in that prior snapshot: 1 more (1.1%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Feline Calicivirus,F-9,Live + Feline Panleukopenia Virus,Johnson Leopard Origin,Live + Feline Rhinotracheitis Virus,F2,Live changes

Signature read: death-coded report count at 15 is the most distinctive stamp on Feline Calicivirus,F-9,Live + Feline Panleukopenia Virus,Johnson Leopard Origin,Live + Feline Rhinotracheitis Virus,F2,Live's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
95
Total Reports
15
Deaths Reported
15.8%
Death-coded share of reports

Active Ingredients

Feline Calicivirus,F-9,LiveFeline Panleukopenia Virus,Johnson Leopard Origin,LiveFeline Rhinotracheitis Virus,F2,Live

Administration Routes

SubcutaneousUnknown

Species Affected

Cat 95

Most Affected Breeds

Domestic Shorthair 70
Domestic Longhair 7
Domestic Mediumhair 4
Siamese 4
Ragdoll 3
Crossbred Feline/cat 2
Cat (other) 1
Maine Coon 1
Himalayan 1
Bengal 1

Most Reported Reactions

Vomiting 25
Lethargy (see also Central nervous system depression in Neurological) 18
Not eating 12
Anorexia 11
Hypothermia 10
Fever 10
Lethargy (see also Central nervous system depression in 'Neurological') 9
Death by euthanasia 8
Diarrhoea 7
Ataxia 7
Death 7
Other abnormal test result NOS 7

Outcome Breakdown

Recovered/Normal
38 (40.0%)
Outcome Unknown
30 (31.6%)
Ongoing
12 (12.6%)
Euthanized
8 (8.4%)
Died
7 (7.4%)

Feline Calicivirus,F-9,Live + Feline Panleukopenia Virus,Johnson Leopard Origin,Live + Feline Rhinotracheitis Virus,F2,Live: high report volume in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Feline Calicivirus,F-9,Live + Feline Panleukopenia Virus,Johnson Leopard Origin,Live + Feline Rhinotracheitis Virus,F2,Live, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar report volume

Nearest other drugs by FDA report count (95 here).

Artificial Tears 95 Flea Spray (Unknown) 95 Chlorpheniramine Maleate 94 Lasix 94

Similar death-coded share

Nearest other drugs by death-coded share (15.8% here), distinct from the volume row.

Erythromycin 15.8% Ursodiol 15.7% Anesthetic 15.7% Florfenicol, Terbinafine, Mometasone Furoate 15.9%

What to do with this drug

  • Compare Feline Calicivirus,F-9,Live + Feline Panleukopenia Virus,Johnson Leopard Origin,Live + Feline Rhinotracheitis Virus,F2,Live's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Feline Calicivirus,F-9,Live + Feline Panleukopenia Virus,Johnson Leopard Origin,Live + Feline Rhinotracheitis Virus,F2,Live (#798 of 2,679 by report volume); death-coded 15.8%. PlainBreed drug row · death-coded report count stamp 15 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →