Drug profile

The FDA adverse-event record for Bovine Parainfluenza 3, Pi3 Ebk-1/Ebht-1 Strain Al-Im;Bovine Respiratory Syncyti

68 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Bovine Parainfluenza 3, Pi3 Ebk-1/Ebht-1 Strain Al-Im;Bovine Respiratory Syncyti. See the species affected, top reactions, and outcomes below.

68
adverse-event reports
95.6%
death-coded share
Cattle
most-reported species
60
Death - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
68
Total Reports
65
Deaths Reported
95.6%
Death Rate

Active Ingredients

Bovine Parainfluenza 3, Pi3 Ebk-1/Ebht-1 Strain Al-Im;Bovine Respiratory Syncyti

Administration Routes

SubcutaneousIntramuscularUnknownOphthalmic

Species Affected

Cattle 68

Most Affected Breeds

Mixed (Cattle) 48
Cattle (other) 8
Aberdeen Angus 5
Crossbred Bovine/Cattle 2
Limousin 2
Jersey 1
Holstein-Friesian also known as Holstein 1
Brahman 1

Most Reported Reactions

Death 60
Lack of efficacy - NOS 46
Necropsy performed 35
Lack of efficacy (bacteria) - Mannheimia haemolytica 8
Lack of efficacy (bacteria) - Histophilus somni 7
Intentional misuse 5
Lack of efficacy (mycoplasma) - NOS 5
Anaphylaxis 4
Suppurative (broncho) pneumonia/pleuropneumonia 4
Pneumonia 4
Found dead 3
Fibrinous (broncho) pneumonia/fibrinous pleuropneumonia 3

Outcome Breakdown

Died
65 (52.8%)
Outcome Unknown
27 (22.0%)
Ongoing
17 (13.8%)
Recovered/Normal
8 (6.5%)
Recovered with Sequela
3 (2.4%)
Euthanized
3 (2.4%)

Bovine Parainfluenza 3, Pi3 Ebk-1/Ebht-1 Strain Al-Im;Bovine Respiratory Syncyti Adverse Event Insights

68 reports name Bovine Parainfluenza 3, Pi3 Ebk-1/Ebht-1 Strain Al-Im;Bovine Respiratory Syncyti; 65 recorded a death outcome (95.6% of reported events, not a population-level mortality rate). Active ingredient: Bovine Parainfluenza 3, Pi3 Ebk-1/Ebht-1 Strain Al-Im;Bovine Respiratory Syncyti. Administration routes: Subcutaneous, Intramuscular, Unknown, Ophthalmic.

By species: Cattle (68 reports). By breed: Mixed (Cattle) (48), Cattle (other) (8), Aberdeen Angus (5).

Leading clinical signs: Death (60), Lack of efficacy - NOS (46), Necropsy performed (35), Lack of efficacy (bacteria) - Mannheimia haemolytica (8). Outcome, 123 coded reports: Died leads at 52.8%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.