Drug profile

The FDA adverse-event record for Feline Leukemia Vaccine, Killed Virus

66 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Feline Leukemia Vaccine, Killed Virus. See the species affected, top reactions, and outcomes below.

66
adverse-event reports
9.1%
death-coded share
Cat
most-reported species
16
Lethargy (see also Central nervous system depression in Neurological) - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
66
Total Reports
6
Deaths Reported
9.1%
Death Rate

Active Ingredients

Feline Leukemia Vaccine, Killed Virus

Administration Routes

SubcutaneousUnknownParenteral

Species Affected

Cat 66

Most Affected Breeds

Domestic Shorthair 48
Domestic Longhair 5
Siamese 4
Domestic Mediumhair 2
Himalayan 1
Crossbred Feline/cat 1
Bengal 1
Cat (unknown) 1
Bombay 1
American Bobtail 1

Most Reported Reactions

Lethargy (see also Central nervous system depression in Neurological) 16
Vomiting 15
Behavioural disorder NOS 12
Pain NOS 9
Not eating 8
Injection site sarcoma 7
Lethargy (see also Central nervous system depression in 'Neurological') 7
Fever 7
Anorexia 6
Hiding 6
Not drinking 6
Emesis (multiple) 6

Outcome Breakdown

Recovered/Normal
25 (37.9%)
Ongoing
18 (27.3%)
Outcome Unknown
16 (24.2%)
Died
4 (6.1%)
Euthanized
2 (3.0%)
Recovered with Sequela
1 (1.5%)

Feline Leukemia Vaccine, Killed Virus Adverse Event Insights

66 reports name Feline Leukemia Vaccine, Killed Virus; 6 recorded a death outcome (9.1% of reported events, not a population-level mortality rate). Active ingredient: Feline Leukemia Vaccine, Killed Virus. Administration routes: Subcutaneous, Unknown, Parenteral.

By species: Cat (66 reports). By breed: Domestic Shorthair (48), Domestic Longhair (5), Siamese (4).

Leading clinical signs: Lethargy (see also Central nervous system depression in Neurological) (16), Vomiting (15), Behavioural disorder NOS (12), Pain NOS (9). Outcome, 66 coded reports: Recovered/Normal leads at 37.9%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.