Drug profile

The FDA adverse-event record for Anesthetic

1,527 FDA reports name Anesthetic, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#135 of 2,679
by report volume (all drugs)
1,527
adverse-event reports
15.7%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Anesthetic ranks #135 of 2679 by total reports (1,527) and #344 of 1130 by death-coded share (15.7%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#135
This drug, reports of 2679
#344
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Anesthetic has 1,527 reports now versus 1,527 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Anesthetic changes

Signature read: death-coded report count at 240 is the most distinctive stamp on Anesthetic's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
1,527
Total Reports
240
Deaths Reported
15.7%
Death-coded share of reports

Active Ingredients

Anesthetic

Administration Routes

UnknownRespiratory (Inhalation)IntravenousSubcutaneousNasalEpiduralIntradermalParenteralTopicalOral

Species Affected

Dog 1,167
Cat 356
Horse 1
Guinea Pig 1
Rabbit 1
Hedgehog 1

Most Affected Breeds

Domestic Shorthair 187
Retriever - Labrador 162
Dog (unknown) 82
Terrier - Bull - American Pit 58
Retriever - Golden 49
Cat (other) 46
Chihuahua 45
Shepherd Dog - German 41
Boxer (German Boxer) 40
Terrier - Yorkshire 34

Most Reported Reactions

Vomiting 299
Lethargy (see also Central nervous system depression in 'Neurological') 293
Anorexia 194
Other abnormal test result NOS 158
Diarrhoea 155
Death 120
Death by euthanasia 110
Elevated alanine aminotransferase (ALT) 107
Decreased appetite 100
Lack of efficacy - NOS 88
Seizure NOS 84
Anaemia NOS 83

Outcome Breakdown

Ongoing
806 (52.7%)
Recovered/Normal
318 (20.8%)
Outcome Unknown
161 (10.5%)
Died
130 (8.5%)
Euthanized
111 (7.3%)
Recovered with Sequela
4 (0.3%)

Anesthetic: high report volume in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Anesthetic, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar death-coded share

Nearest other drugs by death-coded share (15.7% here), distinct from the volume row.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Anesthetic (#135 of 2,679 by report volume); death-coded 15.7%. PlainBreed drug row · death-coded report count stamp 240 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →