Drug profile

The FDA adverse-event record for Da2Pp Vaccine

186 FDA reports name Da2Pp Vaccine, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#555 of 2,679
by report volume (all drugs)
186
adverse-event reports
8.1%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Da2Pp Vaccine ranks #554 of 2679 by total reports (186) and #636 of 1130 by death-coded share (8.1%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#554
This drug, reports of 2679
#636
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Da2Pp Vaccine has 186 reports now versus 184 in that prior snapshot: 2 more (1.1%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Da2Pp Vaccine changes

Signature read: 186 reports place Da2Pp Vaccine in the upper third of FDA AER volume (#555 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
186
Total Reports
15
Deaths Reported
8.1%
Death-coded share of reports

Active Ingredients

Da2Pp Vaccine

Administration Routes

UnknownParenteralSubcutaneous

Species Affected

Dog 186

Most Affected Breeds

Retriever - Labrador 17
Retriever - Golden 10
Crossbred Canine/dog 8
Shepherd Dog - German 7
Dachshund (unspecified) 6
Terrier - Jack Russell 6
Chihuahua 5
Pit Bull 5
Shih Tzu 5
Pug 5

Most Reported Reactions

Emesis 57
Vomiting 54
Lethargy (see also Central nervous system depression in 'Neurological') 45
Anorexia 14
Diarrhoea 13
Ataxia 9
Weight loss 8
Death 8
Lack of efficacy - NOS 8
Other abnormal test result NOS 8
Pruritus 7
Fever 7

Outcome Breakdown

Recovered/Normal
114 (61.3%)
Outcome Unknown
31 (16.7%)
Ongoing
14 (7.5%)
Recovered with Sequela
12 (6.5%)
Died
10 (5.4%)
Euthanized
5 (2.7%)

Da2Pp Vaccine: high report volume in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Da2Pp Vaccine, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar report volume

Nearest other drugs by FDA report count (186 here).

Similar death-coded share

Nearest other drugs by death-coded share (8.1% here), distinct from the volume row.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Da2Pp Vaccine (#555 of 2,679 by report volume); death-coded 8.1%. PlainBreed drug row · report volume stamp 186 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →