Drug profile

The FDA adverse-event record for Thiamazole

653 FDA reports name Thiamazole, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#251 of 2,679
by report volume (all drugs)
653
adverse-event reports
8.1%
death-coded share
Cat
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Thiamazole ranks #251 of 2679 by total reports (653) and #634 of 1130 by death-coded share (8.1%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#251
This drug, reports of 2679
#634
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Thiamazole has 653 reports now versus 644 in that prior snapshot: 9 more (1.4%).

Report change
+9
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Thiamazole changes

Signature read: 653 reports place Thiamazole in the upper third of FDA AER volume (#251 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
653
Total Reports
53
Deaths Reported
8.1%
Death-coded share of reports

Active Ingredients

Thiamazole

Administration Routes

OralUnknownTransdermalTopicalOtherAuricular (Otic)IntradermalRespiratory (Inhalation)

Species Affected

Cat 590
Unknown 42
Human 19
Dog 2

Most Affected Breeds

Domestic Shorthair 389
Cat (unknown) 74
Domestic Longhair 68
Unknown 61
Siamese 17
Maine Coon 11
Ragdoll 9
Cat (other) 5
Russian 4
Burmese 2

Most Reported Reactions

Vomiting 151
Weight loss 111
Lethargy (see also Central nervous system depression in 'Neurological') 69
Elevated alanine aminotransferase (ALT) 66
Lack of efficacy - NOS 51
Anorexia 49
Decreased appetite 47
Excoriation 39
Other abnormal test result NOS 39
Elevated blood urea nitrogen (BUN) 36
Pruritus 32
Low thyroxine (T4) 32

Outcome Breakdown

Outcome Unknown
349 (56.8%)
Recovered/Normal
172 (28.0%)
Ongoing
38 (6.2%)
Died
28 (4.6%)
Euthanized
25 (4.1%)
Recovered with Sequela
2 (0.3%)

Thiamazole: high report volume in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Thiamazole, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar report volume

Nearest other drugs by FDA report count (653 here).

Similar death-coded share

Nearest other drugs by death-coded share (8.1% here), distinct from the volume row.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Thiamazole (#251 of 2,679 by report volume); death-coded 8.1%. PlainBreed drug row · report volume stamp 653 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →