Drug profile

The FDA adverse-event record for Bovine Parainfluenza 3, Pi3 Ebk-1/Ebht-1 Strain Al-Im;Infectious Bovine Rhinotra

Name: Bovine Parainfluenza 3, Pi3 Ebk-1/Ebht-1 Strain Al-Im;Infectious Bovine Rhinotra - FDA Animal Adverse Event Reports
Creator: PlainBreed
License: https://creativecommons.org/publicdomain/zero/1.0/

268 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Bovine Parainfluenza 3, Pi3 Ebk-1/Ebht-1 Strain Al-Im;Infectious Bovine Rhinotra. See the species affected, top reactions, and outcomes below.

268
adverse-event reports: 87.7%
death-coded share: Cattle
most-reported species: 199
Death - top reaction

Compiled by PlainBreed Editorial, Pet Health Editorial Team

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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

268

Total Reports

235

Deaths Reported

87.7%

Death Rate

Active Ingredients

Bovine Parainfluenza 3, Pi3 Ebk-1/Ebht-1 Strain Al-Im;Infectious Bovine Rhinotra

Administration Routes

SubcutaneousIntramuscularUnknownNasal

Species Affected

Cattle 268

Most Affected Breeds

Mixed (Cattle) 221

Aberdeen Angus 21

Holstein-Friesian also known as Holstein 12

Cattle (unknown) 3

Brangus 2

Hereford cattle 2

Crossbred Bovine/Cattle 2

Simmental 1

Cattle (other) 1

Shorthorn (unspecified) 1

Most Reported Reactions

Death 199

Lack of efficacy - NOS 134

Lack of efficacy (bacteria) - NOS 44

INEFFECTIVE, ANTIBIOTIC 21

Necropsy performed 19

CULTURE/TITER DATA ABNORMAL 15

Anaphylactic-type reaction 13

Unexplained death 12

Death by euthanasia 11

Unrelated death 10

Anaphylaxis 9

Lack of efficacy (mycoplasma) - NOS 9

Outcome Breakdown

Died

227 (49.7%)

Outcome Unknown

164 (35.9%)

Recovered/Normal

29 (6.3%)

Ongoing

16 (3.5%)

Euthanized

14 (3.1%)

Recovered with Sequela

7 (1.5%)

Bovine Parainfluenza 3, Pi3 Ebk-1/Ebht-1 Strain Al-Im;Infectious Bovine Rhinotra Adverse Event Insights

268 reports name Bovine Parainfluenza 3, Pi3 Ebk-1/Ebht-1 Strain Al-Im;Infectious Bovine Rhinotra; 235 recorded a death outcome (87.7% of reported events, not a population-level mortality rate). Active ingredient: Bovine Parainfluenza 3, Pi3 Ebk-1/Ebht-1 Strain Al-Im;Infectious Bovine Rhinotra. Administration routes: Subcutaneous, Intramuscular, Unknown, Nasal.

By species: Cattle (268 reports). By breed: Mixed (Cattle) (221), Aberdeen Angus (21), Holstein-Friesian also known as Holstein (12).

Leading clinical signs: Death (199), Lack of efficacy - NOS (134), Lack of efficacy (bacteria) - NOS (44), INEFFECTIVE, ANTIBIOTIC (21). Outcome, 457 coded reports: Died leads at 49.7%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.