Clostr Perf*2/Clos Others*4 Kb
137 adverse event reports submitted to the FDA
Active Ingredients
Administration Routes
Species Affected
Most Affected Breeds
Most Reported Reactions
Outcome Breakdown
Data Summary
| Metric | Value |
|---|---|
| Total adverse event reports | 137 |
| Reports involving death | 120 |
| Case-fatality rate (reported events) | 8760.0% |
| Distinct species in reports | 1 |
| Distinct breeds in reports | 8 |
| Distinct reactions reported | 20 |
| Active ingredients on file | 1 |
Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.
Clostr Perf*2/Clos Others*4 Kb Adverse Event Insights
The FDA Center for Veterinary Medicine database currently holds 137 adverse event reports referencing Clostr Perf*2/Clos Others*4 Kb, including 120 reports in which the animal died — a 8760.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Clostr Perf*2/Clos Others*4 Kb. Reported administration routes include Subcutaneous, Unknown. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.
The species most frequently named in Clostr Perf*2/Clos Others*4 Kb reports are Cattle (137 reports), with Cattle accounting for the largest share. Within those species, Cattle (other) (72), Aberdeen Angus (25), Crossbred Bovine/Cattle (22) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.
The most commonly reported clinical signs associated with Clostr Perf*2/Clos Others*4 Kb are Death (111), Lack of efficacy - NOS (73), Lack of efficacy (bacteria) - NOS (15), Respiratory signs (8). Of the 282 reports with a coded outcome, Died is the leading category at 41.5%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Clostr Perf*2/Clos Others*4 Kb.
Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates
Read our methodology — how this data is sourced, computed, and verified.