Drug profile

The FDA adverse-event record for Anesthetic (Unknown)

642 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Anesthetic (Unknown). See the species affected, top reactions, and outcomes below.

642
adverse-event reports
10.4%
death-coded share
Cat
most-reported species
64
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
642
Total Reports
67
Deaths Reported
10.4%
Death Rate

Active Ingredients

Anesthetic (Unknown)

Administration Routes

UnknownParenteralIntravenousRespiratory (Inhalation)TopicalOralNasalOtherIntramuscularTransdermal

Species Affected

Cat 353
Dog 289

Most Affected Breeds

Domestic Shorthair 175
Cat (unknown) 94
Retriever - Labrador 30
Dog (unknown) 26
Domestic Longhair 19
Domestic Mediumhair 15
Shepherd Dog - German 13
Retriever - Golden 13
Shih Tzu 12
Boxer (German Boxer) 11

Most Reported Reactions

Vomiting 64
Not eating 64
Behavioural disorder NOS 57
Lethargy (see also Central nervous system depression in 'Neurological') 43
Other abnormal test result NOS 38
Dilated pupils 38
Diarrhoea 38
Death by euthanasia 36
Lack of efficacy - NOS 36
Dysphoria 34
Decreased appetite 33
Weight loss 30

Outcome Breakdown

Ongoing
190 (29.5%)
Recovered/Normal
189 (29.4%)
Outcome Unknown
184 (28.6%)
Euthanized
36 (5.6%)
Died
31 (4.8%)
Recovered with Sequela
13 (2.0%)

Anesthetic (Unknown) Adverse Event Insights

642 reports name Anesthetic (Unknown); 67 recorded a death outcome (10.4% of reported events, not a population-level mortality rate). Active ingredient: Anesthetic (Unknown). Administration routes: Unknown, Parenteral, Intravenous, Respiratory (Inhalation).

By species: Cat (353 reports), Dog (289 reports). By breed: Domestic Shorthair (175), Cat (unknown) (94), Retriever - Labrador (30).

Leading clinical signs: Vomiting (64), Not eating (64), Behavioural disorder NOS (57), Lethargy (see also Central nervous system depression in 'Neurological') (43). Outcome, 643 coded reports: Ongoing leads at 29.5%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.