Anesthetic (Unknown)

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642 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
642
Total Reports
67
Deaths Reported
1040.0%
Death Rate

Active Ingredients

Anesthetic (Unknown)

Administration Routes

UnknownParenteralIntravenousRespiratory (Inhalation)TopicalOralNasalOtherIntramuscularTransdermal

Species Affected

Cat 353
Dog 289

Most Affected Breeds

Domestic Shorthair 175
Cat (unknown) 94
Retriever - Labrador 30
Dog (unknown) 26
Domestic Longhair 19
Domestic Mediumhair 15
Shepherd Dog - German 13
Retriever - Golden 13
Shih Tzu 12
Boxer (German Boxer) 11

Most Reported Reactions

Vomiting 64
Not eating 64
Behavioural disorder NOS 57
Lethargy (see also Central nervous system depression in 'Neurological') 43
Other abnormal test result NOS 38
Dilated pupils 38
Diarrhoea 38
Death by euthanasia 36
Lack of efficacy - NOS 36
Dysphoria 34
Decreased appetite 33
Weight loss 30

Outcome Breakdown

Ongoing
190 (29.5%)
Recovered/Normal
189 (29.4%)
Outcome Unknown
184 (28.6%)
Euthanized
36 (5.6%)
Died
31 (4.8%)
Recovered with Sequela
13 (2.0%)

Data Summary

Metric Value
Total adverse event reports 642
Reports involving death 67
Case-fatality rate (reported events) 1040.0%
Distinct species in reports 2
Distinct breeds in reports 20
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Anesthetic (Unknown) Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 642 adverse event reports referencing Anesthetic (Unknown), including 67 reports in which the animal died — a 1040.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Anesthetic (Unknown). Reported administration routes include Unknown, Parenteral, Intravenous, Respiratory (Inhalation). These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Anesthetic (Unknown) reports are Cat (353 reports), Dog (289 reports), with Cat accounting for the largest share. Within those species, Domestic Shorthair (175), Cat (unknown) (94), Retriever - Labrador (30) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Anesthetic (Unknown) are Vomiting (64), Not eating (64), Behavioural disorder NOS (57), Lethargy (see also Central nervous system depression in 'Neurological') (43). Of the 643 reports with a coded outcome, Ongoing is the leading category at 29.5%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Anesthetic (Unknown).

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial