Estriol

622 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

622

Total Reports

Deaths Reported

680.0%

Death Rate

Active Ingredients

Estriol

Administration Routes

OralUnknown

Species Affected

Dog 621

Rat 1

Most Affected Breeds

Crossbred Canine/dog 103

Retriever - Labrador 62

Doberman Pinscher 27

Shepherd Dog - German 24

Dog (unknown) 24

Boxer (German Boxer) 18

Poodle (unspecified) 15

Siberian Husky 14

Schnauzer (unspecified) 13

Pit Bull 13

Most Reported Reactions

Lack of efficacy - NOS 257

Vaginal swelling 82

Vomiting 54

Anorexia 41

Death by euthanasia 37

Diarrhoea 30

Urinary tract infection 26

Weight loss 21

Polydipsia 20

Lethargy (see also Central nervous system depression in 'Neurological') 20

Seizure NOS 19

Vulvitis 17

Outcome Breakdown

Ongoing

81 (32.5%)

Recovered/Normal

65 (26.1%)

Outcome Unknown

60 (24.1%)

Died

26 (10.4%)

Euthanized

16 (6.4%)

Recovered with Sequela

1 (0.4%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.