Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
22
Total Reports
2
Deaths Reported
910.0%
Death Rate
5.6 yr
Avg Age at Report
Average weight at time of report: 37.5 kg (82.7 lbs)
Top Reported Reactions
Vomiting 5
Lethargy (see also Central nervous system depression in 'Neurological') 3
Lack of efficacy (endoparasite) - hookworm 3
Lack of efficacy - NOS 2
Shaking 2
Diarrhoea 2
Emesis (multiple) 2
Lack of efficacy (endoparasite) - heartworm 2
Emesis 1
INEFFECTIVE, ANTIINFLAMMATORY 1
Weight loss 1
Locomotor disturbance 1
Death 1
INEFFECTIVE, ASCARIDS NOS 1
Drooling 1
Most Referenced Drugs
Milbemycin Oxime + Spinosad 5
Doxycycline 2
Lufenuron + Milbemycin Oxime 2
Ivermectin + Pyrantel As Pamoate Salt 2
Moxidectin 2
Meloxicam 1
Pyrantel Pamoate 1
Febantel + Praziquantel + Pyrantel Pamoate 1
Ivermectin 272Mcg, Pyrantel Pamoate 228Mg, Praziquantel 228Mg 1
Methocarbamol 1
Carprofen (Unknown) 1
Fluralaner Chew Tablets 1
Firocoxib 1
Selamectin 1
Insulin Injectable Vial 1
Outcome Breakdown
Recovered/Normal
9 (40.9%)
Outcome Unknown
6 (27.3%)
Ongoing
4 (18.2%)
Died
1 (4.5%)
Euthanized
1 (4.5%)
Recovered with Sequela
1 (4.5%)
Gender Distribution
Male 12 (54.5%)
Female 10 (45.5%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2011 | 1 | |
| 2012 | 4 | |
| 2013 | 1 | |
| 2014 | 2 | |
| 2017 | 3 | |
| 2018 | 3 | |
| 2020 | 1 | |
| 2022 | 1 | |
| 2023 | 1 | |
| 2024 | 1 | |
| 2025 | 4 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #350 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.