Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
22
Total Reports
1
Deaths Reported
450.0%
Death Rate
4.3 yr
Avg Age at Report
Average weight at time of report: 12.7 kg (28.0 lbs)
Top Reported Reactions
Vomiting 10
Diarrhoea 4
Lethargy (see also Central nervous system depression in 'Neurological') 3
Lack of efficacy (endoparasite) - hookworm 3
Elevated alanine aminotransferase (ALT) 2
Pancreatitis 2
Emesis (multiple) 2
Lack of efficacy (protozoa) - Coccidia 2
INEFFECTIVE, HOOKS 2
Non-regenerative anaemia 1
Elevated renal parameters 1
Pruritus 1
Skin lesion NOS 1
Anorexia 1
Other abnormal test result NOS 1
Most Referenced Drugs
Milbemycin Oxime + Spinosad 6
Ivermectin + Pyrantel As Pamoate Salt 3
Milbemycin Oxime + Praziquantel 3
Lotilaner 3
Fluralaner Chew Tablets 2
Fenbendazol Granules 2
Fluralaner 13.64% 12-Week Chew 2
Tylosin Tartrate 1
Firocoxib 1
Lufenuron + Milbemycin Oxime 1
Fipronil, Cyphenothrin 1
Tylosin 1
Milbemycin Oxime 1
Trazadone 1
Grapiprant 1
Outcome Breakdown
Recovered/Normal
12 (54.5%)
Ongoing
5 (22.7%)
Outcome Unknown
3 (13.6%)
Recovered with Sequela
1 (4.5%)
Died
1 (4.5%)
Gender Distribution
Female 14 (63.6%)
Male 8 (36.4%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2012 | 1 | |
| 2013 | 2 | |
| 2014 | 2 | |
| 2015 | 2 | |
| 2017 | 1 | |
| 2018 | 3 | |
| 2019 | 2 | |
| 2020 | 2 | |
| 2021 | 1 | |
| 2022 | 3 | |
| 2023 | 1 | |
| 2024 | 1 | |
| 2025 | 1 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #352 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.