Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
17
Total Reports
1
Deaths Reported
590.0%
Death Rate
3.6 yr
Avg Age at Report
Average weight at time of report: 55.8 kg (123.0 lbs)
Top Reported Reactions
Vomiting 6
Lack of efficacy (endoparasite) - heartworm 3
Lack of efficacy (ectoparasite) - flea 2
Lethargy (see also Central nervous system depression in 'Neurological') 2
Loose stool 1
Other abnormal test result NOS 1
Lack of efficacy (endoparasite) - roundworm NOS 1
Emesis (multiple) 1
Abnormal breathing 1
Heavy breathing 1
Underdose 1
Dehydration 1
Lack of efficacy - NOS 1
Death 1
Appetite loss 1
Most Referenced Drugs
Milbemycin Oxime + Spinosad 6
Ivermectin + Pyrantel As Pamoate Salt 5
Grapiprant 2
Fluralaner Chew Tablets 2
Fluralaner 13.64% 12-Week Chew 2
Oclacitinib 1
Hyposensitization Injections 1
Nitenpyram 1
Permethrin-Imidicloprid-Pyriproxyfen 1
Flumethrin-Imidacloprid 1
Unspecified Natural Flea Spray 1
Unspecified Oatmeal Shampoo 1
Levothyroxine Sodium, Usp 1
Melarsomine Dihydrochloride 1
Dexmedetomidine Hydrochloride 1
Outcome Breakdown
Recovered/Normal
6 (35.3%)
Ongoing
5 (29.4%)
Outcome Unknown
5 (29.4%)
Died
1 (5.9%)
Gender Distribution
Male 10 (58.8%)
Female 7 (41.2%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2013 | 1 | |
| 2017 | 1 | |
| 2018 | 2 | |
| 2019 | 1 | |
| 2020 | 2 | |
| 2021 | 2 | |
| 2022 | 2 | |
| 2023 | 1 | |
| 2024 | 2 | |
| 2025 | 3 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #389 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.