Drug profile

The FDA adverse-event record for Heartworm Injection (Unknown)

58 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Heartworm Injection (Unknown). See the species affected, top reactions, and outcomes below.

58
adverse-event reports
0.0%
death-coded share
Dog
most-reported species
19
Emesis - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
58
Total Reports
0
Deaths Reported
0.0%
Death Rate

Active Ingredients

Heartworm Injection (Unknown)

Administration Routes

ParenteralUnknownOralSubcutaneousIntramuscular

Species Affected

Dog 58

Most Affected Breeds

Chihuahua 6
Shepherd Dog - Australian 4
Pit Bull 4
Retriever - Labrador 3
Spitz - German Pomeranian 3
Shepherd Dog - German 3
Maltese 3
Spaniel - Cocker American 2
Crossbred Canine/dog 2
Boxer (German Boxer) 2

Most Reported Reactions

Emesis 19
Vomiting 13
Lack of efficacy (ectoparasite) - flea 6
Lethargy (see also Central nervous system depression in 'Neurological') 6
Lack of efficacy (endoparasite) - heartworm 6
Shaking 2
Emesis (multiple) 2
Not drinking 2
Not eating 2
Lack of efficacy - NOS 2
INEFFECTIVE, HEARTWORM LARVAE 2
Itching 2

Outcome Breakdown

Recovered/Normal
34 (58.6%)
Outcome Unknown
17 (29.3%)
Ongoing
6 (10.3%)
Recovered with Sequela
1 (1.7%)

Heartworm Injection (Unknown) Adverse Event Insights

58 reports name Heartworm Injection (Unknown); 0 recorded a death outcome (0.0% of reported events, not a population-level mortality rate). Active ingredient: Heartworm Injection (Unknown). Administration routes: Parenteral, Unknown, Oral, Subcutaneous.

By species: Dog (58 reports). By breed: Chihuahua (6), Shepherd Dog - Australian (4), Pit Bull (4).

Leading clinical signs: Emesis (19), Vomiting (13), Lack of efficacy (ectoparasite) - flea (6), Lethargy (see also Central nervous system depression in 'Neurological') (6). Outcome, 58 coded reports: Recovered/Normal leads at 58.6%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.