Tulathromycin Inj Sol

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49 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
49
Total Reports
37
Deaths Reported
7550.0%
Death Rate

Active Ingredients

Tulathromycin Inj Sol

Administration Routes

SubcutaneousUnknownIntramuscularTopicalParenteral

Species Affected

Cattle 44
Unknown 2
Human 2
Pig 1

Most Affected Breeds

Cattle (other) 29
Unknown 4
Aberdeen Angus 4
Crossbred Bovine/Cattle 3
Mixed (Cattle) 3
Cattle (unspecified) 2
Holstein-Friesian also known as Holstein 2
Pig (unknown) 1
Simmental 1

Most Reported Reactions

Death 34
Lack of efficacy - NOS 31
Necropsy performed 4
Lack of efficacy (mycoplasma) - NOS 3
Lack of efficacy (bacteria) - Histophilus somni 3
Recumbency 3
Anaphylaxis 3
Fibrinous (broncho) pneumonia/fibrinous pleuropneumonia 2
Hypersensitivity reaction 2
Death by euthanasia 2
Laboured breathing 2
Physical label missing 1

Outcome Breakdown

Died
36 (44.4%)
Ongoing
22 (27.2%)
Outcome Unknown
16 (19.8%)
Recovered/Normal
5 (6.2%)
Euthanized
2 (2.5%)

Data Summary

Metric Value
Total adverse event reports 49
Reports involving death 37
Case-fatality rate (reported events) 7550.0%
Distinct species in reports 4
Distinct breeds in reports 9
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Tulathromycin Inj Sol Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 49 adverse event reports referencing Tulathromycin Inj Sol, including 37 reports in which the animal died — a 7550.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Tulathromycin Inj Sol. Reported administration routes include Subcutaneous, Unknown, Intramuscular, Topical. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Tulathromycin Inj Sol reports are Cattle (44 reports), Unknown (2 reports), Human (2 reports), with Cattle accounting for the largest share. Within those species, Cattle (other) (29), Unknown (4), Aberdeen Angus (4) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Tulathromycin Inj Sol are Death (34), Lack of efficacy - NOS (31), Necropsy performed (4), Lack of efficacy (mycoplasma) - NOS (3). Of the 81 reports with a coded outcome, Died is the leading category at 44.4%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Tulathromycin Inj Sol.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial