Drug profile

The FDA adverse-event record for Chlorhexidine Gluconate + Phytosphingosine Salicyloyl

69 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Chlorhexidine Gluconate + Phytosphingosine Salicyloyl. See the species affected, top reactions, and outcomes below.

69
adverse-event reports
0.0%
death-coded share
Dog
most-reported species
9
Erythema (for urticaria see Immune SOC) - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
69
Total Reports
0
Deaths Reported
0.0%
Death Rate

Active Ingredients

Chlorhexidine GluconatePhytosphingosine Salicyloyl

Administration Routes

TopicalUnknown

Species Affected

Dog 56
Cat 9
Human 4

Most Affected Breeds

Crossbred Canine/dog 11
Chihuahua 9
Terrier - Yorkshire 5
Cat (unknown) 4
Unknown 4
Mixed (Dog) 3
Domestic Shorthair 3
Retriever - Labrador 3
Retriever - Golden 3
Havanese 2

Most Reported Reactions

Erythema (for urticaria see Immune SOC) 9
Pruritus 9
Application site erythema 8
Anorexia 6
Skin irritation 4
Vocalisation 4
Lethargy (see also Central nervous system depression in 'Neurological') 4
Hypoglycaemia 4
Rolling 3
Behavioural disorder NOS 3
Application site irritation 3
Erythematous rash 3

Outcome Breakdown

Recovered/Normal
40 (58.0%)
Outcome Unknown
12 (17.4%)
Ongoing
10 (14.5%)
Recovered with Sequela
7 (10.1%)

Chlorhexidine Gluconate + Phytosphingosine Salicyloyl Adverse Event Insights

69 reports name Chlorhexidine Gluconate + Phytosphingosine Salicyloyl; 0 recorded a death outcome (0.0% of reported events, not a population-level mortality rate). Active ingredients: Chlorhexidine Gluconate, Phytosphingosine Salicyloyl. Administration routes: Topical, Unknown.

By species: Dog (56 reports), Cat (9 reports), Human (4 reports). By breed: Crossbred Canine/dog (11), Chihuahua (9), Terrier - Yorkshire (5).

Leading clinical signs: Erythema (for urticaria see Immune SOC) (9), Pruritus (9), Application site erythema (8), Anorexia (6). Outcome, 69 coded reports: Recovered/Normal leads at 58.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.