Drug profile

The FDA adverse-event record for Chlorhexidine Gluconate + Phytosphingosine Salicyloyl

69 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Chlorhexidine Gluconate + Phytosphingosine Salicyloyl. Species, reactions, and outcomes follow.

#937 of 2,679
by report volume (all drugs)
69
adverse-event reports
0.0%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Chlorhexidine Gluconate + Phytosphingosine Salicyloyl ranks #937 of 2679 by total reports (69) and #1101 of 1130 by death-coded share (0.0%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#937
This drug, reports of 2679
#1101
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Chlorhexidine Gluconate + Phytosphingosine Salicyloyl has 69 reports now versus 69 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Chlorhexidine Gluconate + Phytosphingosine Salicyloyl changes

Signature read: Chlorhexidine Gluconate + Phytosphingosine Salicyloyl's 0.0% death-coded share is among the lowest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
69
Total Reports
0
Deaths Reported
0.0%
Death-coded share of reports

Active Ingredients

Chlorhexidine GluconatePhytosphingosine Salicyloyl

Administration Routes

TopicalUnknown

Species Affected

Dog 56
Cat 9
Human 4

Most Affected Breeds

Crossbred Canine/dog 11
Chihuahua 9
Terrier - Yorkshire 5
Cat (unknown) 4
Unknown 4
Mixed (Dog) 3
Retriever - Labrador 3
Domestic Shorthair 3
Retriever - Golden 3
Bulldog 2

Most Reported Reactions

Erythema (for urticaria see Immune SOC) 9
Pruritus 9
Application site erythema 8
Anorexia 6
Vocalisation 4
Skin irritation 4
Lethargy (see also Central nervous system depression in 'Neurological') 4
Hypoglycaemia 4
Rolling 3
Behavioural disorder NOS 3
Application site irritation 3
Erythematous rash 3

Outcome Breakdown

Recovered/Normal
40 (58.0%)
Outcome Unknown
12 (17.4%)
Ongoing
10 (14.5%)
Recovered with Sequela
7 (10.1%)

Chlorhexidine Gluconate + Phytosphingosine Salicyloyl: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Nationwide drugs with similar profiles

Two openFDA-derived peer sets for Chlorhexidine Gluconate + Phytosphingosine Salicyloyl, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar report volume

Nearest other drugs by FDA report count (69 here).

Similar death-coded share

Nearest other drugs by death-coded share (0.0% here), distinct from the volume row.

What to do with this drug

  • Compare Chlorhexidine Gluconate + Phytosphingosine Salicyloyl's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Chlorhexidine Gluconate + Phytosphingosine Salicyloyl (#937 of 2,679 by report volume); death-coded 0.0%. PlainBreed drug row · death-coded share stamp 0.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →