Fipronil, Cyphenothrin
135 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
135
Total Reports
6
Deaths Reported
440.0%
Death Rate
Active Ingredients
Fipronil, Cyphenothrin
Administration Routes
TopicalOralCutaneous
Species Affected
Dog 135
Most Affected Breeds
Bichon Frise 12
Shih Tzu 11
Retriever - Labrador 11
Retriever - Golden 10
Shepherd Dog - Australian 6
Chihuahua 6
Crossbred Canine/dog 6
Pug 6
Shepherd Dog - German 5
Spaniel - Cocker American 4
Most Reported Reactions
Lethargy (see also Central nervous system depression in 'Neurological') 30
Restlessness 23
Pruritus 23
Panting 16
Anxiety 15
Diarrhoea 15
Emesis 15
Twitching 12
Application site pruritus 11
Vocalisation 11
Hyperactivity 10
Anorexia 10
Outcome Breakdown
Recovered/Normal
84 (62.2%)
Ongoing
33 (24.4%)
Outcome Unknown
11 (8.1%)
Euthanized
5 (3.7%)
Recovered with Sequela
1 (0.7%)
Died
1 (0.7%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.