Fipronil 9.8%/S-Methoprene 8.8%/Cyphenothrin 5.2% Squeeze-On
556 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
556
Total Reports
2
Deaths Reported
40.0%
Death Rate
Active Ingredients
Fipronil 9.8%/S-Methoprene 8.8%/Cyphenothrin 5.2% Squeeze-On
Administration Routes
UnknownOtherOralSubconjunctivalTopical
Species Affected
Dog 556
Most Affected Breeds
Shih Tzu 78
Crossbred Canine/dog 42
Bichon Frise 39
Maltese 38
Retriever - Labrador 24
Chihuahua 23
Poodle - Toy 20
Retriever - Golden 19
Terrier - Yorkshire 18
Spitz - German Pomeranian 15
Most Reported Reactions
Restlessness 139
Behavioural disorder NOS 79
Hyperactivity 71
Itching 68
Scratching 68
Twitching 60
Lethargy (see also Central nervous system depression in 'Neurological') 53
Vomiting 52
Agitation 45
Vocalisation 39
Anxiety 39
Panting 38
Outcome Breakdown
Recovered/Normal
271 (48.7%)
Outcome Unknown
266 (47.8%)
Ongoing
16 (2.9%)
Euthanized
1 (0.2%)
Recovered with Sequela
1 (0.2%)
Died
1 (0.2%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.