Drug profile

The FDA adverse-event record for Ivermectin/Pyrantel Chew. Dog 136Mcg/114Mg

541 FDA reports name Ivermectin/Pyrantel Chew. Dog 136Mcg/114Mg, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#286 of 2,679
by report volume (all drugs)
541
adverse-event reports
0.4%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Ivermectin/Pyrantel Chew. Dog 136Mcg/114Mg ranks #286 of 2679 by total reports (541) and #1097 of 1130 by death-coded share (0.4%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#286
This drug, reports of 2679
#1097
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Ivermectin/Pyrantel Chew. Dog 136Mcg/114Mg has 541 reports now versus 541 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Ivermectin/Pyrantel Chew. Dog 136Mcg/114Mg changes

Signature read: 541 reports place Ivermectin/Pyrantel Chew. Dog 136Mcg/114Mg in the upper third of FDA AER volume (#286 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
541
Total Reports
2
Deaths Reported
0.4%
Death-coded share of reports

Active Ingredients

Ivermectin/Pyrantel Chew. Dog 136Mcg/114Mg

Administration Routes

OralUnknownSubcutaneous

Species Affected

Dog 477
Unknown 63
Human 1

Most Affected Breeds

Crossbred Canine/dog 101
Unknown 64
Beagle 53
Retriever - Labrador 42
Dog (other) 25
Collie - Border 15
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 13
Retriever - Golden 13
Hound - Basset 11
Spaniel - Cocker American 11

Most Reported Reactions

Digestive tract disorder NOS 265
INEFFECTIVE, HEARTWORM LARVAE 199
Cardiac disorder NOS 133
Lack of efficacy (endoparasite) - hookworm 128
INEFFECTIVE, ASCARIDS NOS 110
No sign 58
Lack of efficacy - NOS 46
Tablets, Abnormal 32
Vomiting 31
Containers, Damaged 28
Diarrhoea 23
Lack of efficacy (protozoa) - Coccidia 13

Outcome Breakdown

Outcome Unknown
312 (64.9%)
Recovered with Sequela
131 (27.2%)
Recovered/Normal
31 (6.4%)
Ongoing
5 (1.0%)
Died
2 (0.4%)

Ivermectin/Pyrantel Chew. Dog 136Mcg/114Mg: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Ivermectin/Pyrantel Chew. Dog 136Mcg/114Mg, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

  • Compare Ivermectin/Pyrantel Chew. Dog 136Mcg/114Mg's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Ivermectin/Pyrantel Chew. Dog 136Mcg/114Mg (#286 of 2,679 by report volume); death-coded 0.4%. PlainBreed drug row · report volume stamp 541 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →