Drug profile

The FDA adverse-event record for Ivermectin/Pyrantel Chew. Dog 136Mcg/114Mg

541 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Ivermectin/Pyrantel Chew. Dog 136Mcg/114Mg. See the species affected, top reactions, and outcomes below.

541
adverse-event reports
0.4%
death-coded share
Dog
most-reported species
265
Digestive tract disorder NOS - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
541
Total Reports
2
Deaths Reported
0.4%
Death Rate

Active Ingredients

Ivermectin/Pyrantel Chew. Dog 136Mcg/114Mg

Administration Routes

OralUnknownSubcutaneous

Species Affected

Dog 477
Unknown 63
Human 1

Most Affected Breeds

Crossbred Canine/dog 101
Unknown 64
Beagle 53
Retriever - Labrador 42
Dog (other) 25
Collie - Border 15
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 13
Retriever - Golden 13
Hound - Basset 11
Spaniel - Cocker American 11

Most Reported Reactions

Digestive tract disorder NOS 265
INEFFECTIVE, HEARTWORM LARVAE 199
Cardiac disorder NOS 133
Lack of efficacy (endoparasite) - hookworm 128
INEFFECTIVE, ASCARIDS NOS 110
No sign 58
Lack of efficacy - NOS 46
Tablets, Abnormal 32
Vomiting 31
Containers, Damaged 28
Diarrhoea 23
Lack of efficacy (protozoa) - Coccidia 13

Outcome Breakdown

Outcome Unknown
312 (64.9%)
Recovered with Sequela
131 (27.2%)
Recovered/Normal
31 (6.4%)
Ongoing
5 (1.0%)
Died
2 (0.4%)

Ivermectin/Pyrantel Chew. Dog 136Mcg/114Mg Adverse Event Insights

541 reports name Ivermectin/Pyrantel Chew. Dog 136Mcg/114Mg; 2 recorded a death outcome (0.4% of reported events, not a population-level mortality rate). Active ingredient: Ivermectin/Pyrantel Chew. Dog 136Mcg/114Mg. Administration routes: Oral, Unknown, Subcutaneous.

By species: Dog (477 reports), Unknown (63 reports), Human (1 reports). By breed: Crossbred Canine/dog (101), Unknown (64), Beagle (53).

Leading clinical signs: Digestive tract disorder NOS (265), INEFFECTIVE, HEARTWORM LARVAE (199), Cardiac disorder NOS (133), Lack of efficacy (endoparasite) - hookworm (128). Outcome, 481 coded reports: Outcome Unknown leads at 64.9%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.