Deslorelin

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315 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
315
Total Reports
16
Deaths Reported
510.0%
Death Rate

Active Ingredients

Deslorelin

Administration Routes

SubcutaneousUnknownParenteralIntradermalOralVaginalIntramuscular

Species Affected

Ferret 166
Unknown 140
Dog 2
Chicken 2
Horse 2
Parrot 1
Other Birds 1
Human 1

Most Affected Breeds

Unknown 158
Domestic ferret (Pet ferret) 148
Chicken (unknown) 2
Chow Chow 1
Ferret (unknown) 1
Parrot (unknown) 1
Other Birds (unknown) 1
Brittany 1
Quarter Horse 1
Thoroughbred 1

Most Reported Reactions

Lack of efficacy - NOS 96
Implant, Abnormal 63
Administration device NOS, malfunction 39
Applicator, Abnormal 23
Containers, Damaged 18
Administration device NOS, abnormal 18
Lack of efficacy 16
Difficulty of Use 10
Implant site reaction NOS 8
Death 7
Hypoglycaemia 5
Aggression 5

Outcome Breakdown

Outcome Unknown
117 (66.1%)
Recovered/Normal
35 (19.8%)
Died
10 (5.6%)
Ongoing
9 (5.1%)
Euthanized
6 (3.4%)

Data Summary

Metric Value
Total adverse event reports 315
Reports involving death 16
Case-fatality rate (reported events) 510.0%
Distinct species in reports 8
Distinct breeds in reports 10
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Deslorelin Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 315 adverse event reports referencing Deslorelin, including 16 reports in which the animal died — a 510.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Deslorelin. Reported administration routes include Subcutaneous, Unknown, Parenteral, Intradermal. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Deslorelin reports are Ferret (166 reports), Unknown (140 reports), Dog (2 reports), with Ferret accounting for the largest share. Within those species, Unknown (158), Domestic ferret (Pet ferret) (148), Chicken (unknown) (2) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Deslorelin are Lack of efficacy - NOS (96), Implant, Abnormal (63), Administration device NOS, malfunction (39), Applicator, Abnormal (23). Of the 177 reports with a coded outcome, Outcome Unknown is the leading category at 66.1%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Deslorelin.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial