Drug profile

The FDA adverse-event record for Deslorelin

315 FDA reports name Deslorelin, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#407 of 2,679
by report volume (all drugs)
315
adverse-event reports
5.1%
death-coded share
Ferret
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Deslorelin ranks #407 of 2679 by total reports (315) and #790 of 1130 by death-coded share (5.1%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#407
This drug, reports of 2679
#790
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Deslorelin has 315 reports now versus 315 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Deslorelin changes

Signature read: 315 reports place Deslorelin in the upper third of FDA AER volume (#407 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
315
Total Reports
16
Deaths Reported
5.1%
Death-coded share of reports

Active Ingredients

Deslorelin

Administration Routes

SubcutaneousUnknownParenteralIntradermalOralVaginalIntramuscular

Species Affected

Ferret 166
Unknown 140
Dog 2
Chicken 2
Horse 2
Parrot 1
Other Birds 1
Human 1

Most Affected Breeds

Unknown 158
Domestic ferret (Pet ferret) 148
Chicken (unknown) 2
Chow Chow 1
Ferret (unknown) 1
Parrot (unknown) 1
Other Birds (unknown) 1
Brittany 1
Quarter Horse 1
Thoroughbred 1

Most Reported Reactions

Lack of efficacy - NOS 96
Implant, Abnormal 63
Administration device NOS, malfunction 39
Applicator, Abnormal 23
Containers, Damaged 18
Administration device NOS, abnormal 18
Lack of efficacy 16
Difficulty of Use 10
Implant site reaction NOS 8
Death 7
Hypoglycaemia 5
Aggression 5

Outcome Breakdown

Outcome Unknown
117 (66.1%)
Recovered/Normal
35 (19.8%)
Died
10 (5.6%)
Ongoing
9 (5.1%)
Euthanized
6 (3.4%)

Deslorelin: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Deslorelin, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar death-coded share

Nearest other drugs by death-coded share (5.1% here), distinct from the volume row.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Deslorelin (#407 of 2,679 by report volume); death-coded 5.1%. PlainBreed drug row · report volume stamp 315 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →