Drug profile

The FDA adverse-event record for Deslorelin

315 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Deslorelin. See the species affected, top reactions, and outcomes below.

315
adverse-event reports
5.1%
death-coded share
Ferret
most-reported species
96
Lack of efficacy - NOS - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
315
Total Reports
16
Deaths Reported
5.1%
Death Rate

Active Ingredients

Deslorelin

Administration Routes

SubcutaneousUnknownParenteralIntradermalOralVaginalIntramuscular

Species Affected

Ferret 166
Unknown 140
Dog 2
Chicken 2
Horse 2
Parrot 1
Other Birds 1
Human 1

Most Affected Breeds

Unknown 158
Domestic ferret (Pet ferret) 148
Chicken (unknown) 2
Chow Chow 1
Ferret (unknown) 1
Parrot (unknown) 1
Other Birds (unknown) 1
Brittany 1
Quarter Horse 1
Thoroughbred 1

Most Reported Reactions

Lack of efficacy - NOS 96
Implant, Abnormal 63
Administration device NOS, malfunction 39
Applicator, Abnormal 23
Containers, Damaged 18
Administration device NOS, abnormal 18
Lack of efficacy 16
Difficulty of Use 10
Implant site reaction NOS 8
Death 7
Hypoglycaemia 5
Aggression 5

Outcome Breakdown

Outcome Unknown
117 (66.1%)
Recovered/Normal
35 (19.8%)
Died
10 (5.6%)
Ongoing
9 (5.1%)
Euthanized
6 (3.4%)

Deslorelin Adverse Event Insights

315 reports name Deslorelin; 16 recorded a death outcome (5.1% of reported events, not a population-level mortality rate). Active ingredient: Deslorelin. Administration routes: Subcutaneous, Unknown, Parenteral, Intradermal.

By species: Ferret (166 reports), Unknown (140 reports), Dog (2 reports). By breed: Unknown (158), Domestic ferret (Pet ferret) (148), Chicken (unknown) (2).

Leading clinical signs: Lack of efficacy - NOS (96), Implant, Abnormal (63), Administration device NOS, malfunction (39), Applicator, Abnormal (23). Outcome, 177 coded reports: Outcome Unknown leads at 66.1%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.