Drug profile

The FDA adverse-event record for Cloxacillin Benz Intramam Dc

157 FDA reports name Cloxacillin Benz Intramam Dc, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#612 of 2,679
by report volume (all drugs)
157
adverse-event reports
52.9%
death-coded share
Cattle
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Cloxacillin Benz Intramam Dc ranks #612 of 2679 by total reports (157) and #53 of 1130 by death-coded share (52.9%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#612
This drug, reports of 2679
#53
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Cloxacillin Benz Intramam Dc has 157 reports now versus 155 in that prior snapshot: 2 more (1.3%).

Report change
+2
Death-coded reports
+2
Death-coded share
+0.6 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Cloxacillin Benz Intramam Dc changes

Signature read: Cloxacillin Benz Intramam Dc's 52.9% death-coded share is among the highest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
157
Total Reports
83
Deaths Reported
52.9%
Death-coded share of reports

Active Ingredients

Cloxacillin Benz Intramam Dc

Administration Routes

IntramammaryUnknownSubcutaneousOther

Species Affected

Cattle 111
Unknown 44
Goat 2

Most Affected Breeds

Holstein-Friesian also known as Holstein 73
Unknown 44
Cattle (other) 31
Jersey 5
Cattle (unspecified) 2
Goat (other) 2

Most Reported Reactions

Death 76
Lack of efficacy (bacteria) - NOS 31
Difficulty of Use 30
Product problem 27
Lack of efficacy - NOS 21
Mastitis NOS 20
Residues in milk 13
Abortion 12
Mammary gland disorder NOS 10
Product Defect, General 9
Uncoded sign 8
NT - Abnormal necropsy finding NOS 6

Outcome Breakdown

Died
81 (49.4%)
Outcome Unknown
41 (25.0%)
Ongoing
21 (12.8%)
Recovered/Normal
17 (10.4%)
Euthanized
4 (2.4%)

Cloxacillin Benz Intramam Dc: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Cloxacillin Benz Intramam Dc, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

  • Compare Cloxacillin Benz Intramam Dc's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Cloxacillin Benz Intramam Dc (#612 of 2,679 by report volume); death-coded 52.9%. PlainBreed drug row · death-coded share stamp 52.9% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →