Drug profile

The FDA adverse-event record for Chlortetracycline Calcium Complex (Biomass)

76 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Chlortetracycline Calcium Complex (Biomass). Species, reactions, and outcomes follow.

#900 of 2,679
by report volume (all drugs)
76
adverse-event reports
53.9%
death-coded share
Cattle
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Chlortetracycline Calcium Complex (Biomass) ranks #898 of 2679 by total reports (76) and #50 of 1130 by death-coded share (53.9%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#898
This drug, reports of 2679
#50
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Chlortetracycline Calcium Complex (Biomass) has 76 reports now versus 76 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Chlortetracycline Calcium Complex (Biomass) changes

Signature read: Chlortetracycline Calcium Complex (Biomass)'s 53.9% death-coded share is among the highest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
76
Total Reports
41
Deaths Reported
53.9%
Death-coded share of reports

Active Ingredients

Chlortetracycline Calcium Complex (Biomass)

Administration Routes

OralUnknownSubcutaneous

Species Affected

Cattle 53
Unknown 19
Horse 2
Chicken 1
Pig 1

Most Affected Breeds

Mixed (Cattle) 44
Unknown 19
Cattle (other) 5
Aberdeen Angus 2
Horse (unknown) 2
Chicken (unknown) 1
Holstein-Friesian also known as Holstein 1
Pig (unknown) 1
Hereford cattle 1

Most Reported Reactions

Death 35
Lack of efficacy - NOS 32
INEFFECTIVE, ANTIBIOTIC 15
Color, Abnormal 5
Containers, Damaged 4
Death by euthanasia 3
Closure, Abnormal 3
CULTURE/TITER DATA ABNORMAL 3
Appearance, Abnormal 3
Odor, Abnormal 2
Underdose 2
Contamination, Foreign Object 2

Outcome Breakdown

Died
39 (42.4%)
Outcome Unknown
35 (38.0%)
Recovered/Normal
6 (6.5%)
Ongoing
5 (5.4%)
Euthanized
4 (4.3%)
Recovered with Sequela
3 (3.3%)

Chlortetracycline Calcium Complex (Biomass): high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Nationwide drugs with similar profiles

Two openFDA-derived peer sets for Chlortetracycline Calcium Complex (Biomass), both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar report volume

Nearest other drugs by FDA report count (76 here).

Similar death-coded share

Nearest other drugs by death-coded share (53.9% here), distinct from the volume row.

What to do with this drug

  • Compare Chlortetracycline Calcium Complex (Biomass)'s report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Chlortetracycline Calcium Complex (Biomass) (#900 of 2,679 by report volume); death-coded 53.9%. PlainBreed drug row · death-coded share stamp 53.9% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →