Drug profile

The FDA adverse-event record for Gonadorelin Hydrochloride

58 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Gonadorelin Hydrochloride. Species, reactions, and outcomes follow.

#1030 of 2,679
by report volume (all drugs)
58
adverse-event reports
8.6%
death-coded share
Cattle
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Gonadorelin Hydrochloride ranks #1025 of 2679 by total reports (58) and #612 of 1130 by death-coded share (8.6%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1025
This drug, reports of 2679
#612
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Gonadorelin Hydrochloride has 58 reports now versus 58 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Gonadorelin Hydrochloride changes

Signature read: report volume at 58 is the most distinctive stamp on Gonadorelin Hydrochloride's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
58
Total Reports
5
Deaths Reported
8.6%
Death-coded share of reports

Active Ingredients

Gonadorelin Hydrochloride

Administration Routes

IntramuscularUnknownSubcutaneous

Species Affected

Cattle 39
Unknown 16
Human 3

Most Affected Breeds

Unknown 19
Mixed (Cattle) 17
Aberdeen Angus 9
Cattle (other) 5
Holstein-Friesian also known as Holstein 3
Cattle (unspecified) 1
Hereford cattle 1
Simmental 1
Texas Longhorn 1
Red Angus 1

Most Reported Reactions

Lack of efficacy - NOS 30
INEFFECTIVE, ESTRUS SYNCHRONIZ 9
Uncoded sign 4
Reduced conception rate 3
No sign 3
Death 3
Caps, Abnormal 2
Vials, Leaking 2
Underfilling, Vials 2
Accidental exposure 2
Injection site reaction NOS 2
Physical label missing 2

Outcome Breakdown

Outcome Unknown
36 (70.6%)
Recovered/Normal
5 (9.8%)
Died
4 (7.8%)
Ongoing
3 (5.9%)
Euthanized
2 (3.9%)
Recovered with Sequela
1 (2.0%)

Gonadorelin Hydrochloride Adverse Event Insights

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Nationwide drugs with similar profiles

Two openFDA-derived peer sets for Gonadorelin Hydrochloride, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar report volume

Nearest other drugs by FDA report count (58 here).

Similar death-coded share

Nearest other drugs by death-coded share (8.6% here), distinct from the volume row.

What to do with this drug

  • Compare Gonadorelin Hydrochloride's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Gonadorelin Hydrochloride (#1030 of 2,679 by report volume); death-coded 8.6%. PlainBreed drug row · report volume stamp 58 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →