Total Reports
6
FDA CVM filings
Dog /
2026 FDA CVM data 6 reports on file official source
Spitz - German Medium size — FDA Adverse Event Profile
Adverse-event records and label data for Spitz - German Medium size (Dog), sourced from the FDA Center for Veterinary Medicine. Refreshed as new reports are filed. Cite PlainBreed when reusing this analysis.
Spitz - German Medium size (Dog) has 6 FDA adverse event reports on record, with 1 deaths reported (1670.0% death rate) — ranking #479 by report volume. The most frequently reported reaction is Vomiting (1 cases). The top associated drug is Milbemycin Oxime + Spinosad. Average age at report: 7.8 years.
Deaths Reported
1
of 6 reports
Death Rate
1670.0%
death-coded share
Avg Age at Report
7.8 yr
13.1 kg avg weight
Death-Coded Outcome Share
Spitz - German Medium size death-coded reports 100.0%
Database median
1670.0% of 6 reports involved a death outcome. Read alongside breed popularity, veterinary access, and owner awareness — these shape how many events ever reach the FDA. The 12% comparison line is the rough cross-breed median in the FDA CVM database; values above suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 13.1 kg (28.9 lbs)
Top Reported Reactions
Vomiting 1
Excessive thirst 1
Seizure NOS 1
Disorientation 1
Elevated temperature 1
Emesis 1
Lethargy (see also Central nervous system depression in 'Neurological') 1
Weight gain 1
Other abnormal test result NOS 1
Skin disorders NOS 1
Lack of efficacy (tick) 1
Inappetence 1
Weight loss 1
Elevated liver enzymes NOS 1
Elevated alanine aminotransferase (ALT) 1
Most Referenced Drugs
Milbemycin Oxime + Spinosad 2
Trilostane 2
Vaccines (Unknown) 1
Prednisolone Trimeprazine Tartrate 1
Afoxolaner 11.3 Mg Chewable Tablets 1
Carprofen 1
Moxidectin + Pyrantel + Sarolaner 1
Outcome Breakdown
Recovered/Normal
3 (50.0%)
Outcome Unknown
2 (33.3%)
Died
1 (16.7%)
Gender Distribution
Female 3 (50.0%)
Male 3 (50.0%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2013 | 1 | |
| 2014 | 2 | |
| 2016 | 1 | |
| 2024 | 1 | |
| 2025 | 1 | |
Spitz - German Medium size Pet Health Insights
Across the FDA Center for Veterinary Medicine adverse event database, Spitz - German Medium size accounts for 6 submitted reports and currently ranks #479 by report volume within the dog population. Of those reports, 1 involved a death outcome — a 1670.0% case-fatality figure calculated directly from the underlying FDA records rather than from external mortality studies. The mean age at time of reporting is 7.8 years, with an average recorded body weight of 13.1 kg (28.9 lbs). These figures reflect the voluntary reporting pool only and should be read alongside breed popularity, veterinary access, and owner awareness — all of which shape how many events ever reach the FDA.
The most frequently reported clinical signs for Spitz - German Medium size are Vomiting (1 reports), Excessive thirst (1 reports), Seizure NOS (1 reports), together capturing a substantial share of the top-reaction traffic seen in this breed's record. On the product side, Milbemycin Oxime + Spinosad appears in 2 reports and is the single most-referenced drug, followed by Trilostane (2) and Vaccines (Unknown) (1). Counts like these surface which therapeutic classes dominate the reporting stream — useful context when comparing reactions across breeds of the same dog species.
Outcome coding on the 6 reports with a recorded status is dominated by Recovered/Normal (50.0% of coded outcomes). Annual submission volume ranges from 2,013 to 2,025 reports across the 5 years on file, indicating the reporting trend is shaped as much by awareness cycles as by underlying clinical events. Because FDA adverse event reports describe correlation rather than causation, these numbers are most useful as a signal of where to ask further questions with a veterinarian — not as a standalone risk score for any individual dog.
Understanding Spitz - German Medium size Adverse Event Data
Spitz - German Medium size has 6 adverse event reports on file. Lower report volumes may reflect a less common breed, lower reporting rates, or genuinely fewer adverse events.
The 1670.0% death rate is above average, though this statistic should be interpreted cautiously. Death reports may be overrepresented because serious outcomes are more likely to be reported than mild reactions.
The most frequently referenced drug in adverse reports is Milbemycin Oxime + Spinosad, appearing in 2 reports. This may indicate widespread use of the medication rather than a specific safety concern for Spitz - German Medium size.
Other Dog Breeds
Retriever - Labrador
90,806 reports · 360.0% death rate
Crossbred Canine/dog
68,210 reports · 320.0% death rate
Dog (unknown)
47,381 reports · 870.0% death rate
Retriever - Golden
34,475 reports · 370.0% death rate
Shepherd Dog - German
31,142 reports · 430.0% death rate
Chihuahua
30,657 reports · 420.0% death rate
Frequently Asked Questions
How many FDA adverse event reports involve Spitz - German Medium size? ▼
There are 6 adverse event reports involving Spitz - German Medium size in the FDA database, with 1 reports involving death (1670.0% death rate). Spitz - German Medium size ranks #479 by report volume.
What are the most common adverse reactions reported for Spitz - German Medium size? ▼
The most commonly reported adverse reactions for Spitz - German Medium size are Vomiting (1 reports), Excessive thirst (1 reports), Seizure NOS (1 reports), Disorientation (1 reports), Elevated temperature (1 reports).
What drugs are most frequently associated with Spitz - German Medium size adverse events? ▼
The drugs most frequently referenced in Spitz - German Medium size adverse event reports are Milbemycin Oxime + Spinosad (2 reports), Trilostane (2 reports), Vaccines (Unknown) (1 reports), Prednisolone Trimeprazine Tartrate (1 reports), Afoxolaner 11.3 Mg Chewable Tablets (1 reports).
What is the average age of Spitz - German Medium size in adverse event reports? ▼
The average age of Spitz - German Medium size at the time of adverse event reports is 7.8 years, with an average weight of 13.1 kg (28.9 lbs).
Does a high number of adverse event reports mean Spitz - German Medium size is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Spitz - German Medium size safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Guides & Resources
Understanding Adverse Events
What FDA reports are and how they are collected
Breed-Specific Risks
Why some breeds appear in more adverse event reports
Pet Medication Safety
Evaluating medication risks using FDA data
Most Reported Medications
Drugs that appear most in adverse event reports
How FDA CVM Tracks Events
The reporting process and database limitations
Related Data Sources
Data Sources & Methodology
Adverse event data sourced from the FDA Center for Veterinary Medicine via the openFDA Animal & Veterinary Adverse Events API. Reports are voluntarily submitted by pet owners, veterinarians, and product manufacturers.
Spitz - German Medium size ranks #479 by total report volume. Death rate (1670.0%) reflects the proportion of reports involving death and should not be interpreted as a breed-specific mortality rate. Reporting biases, breed popularity, and veterinary access all influence report counts.
Read our methodology — how this data is sourced, computed, and verified.
Related
Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial