Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
11
Total Reports
1
Deaths Reported
910.0%
Death Rate
4.8 yr
Avg Age at Report
Average weight at time of report: 31.1 kg (68.6 lbs)
Top Reported Reactions
Emesis 2
Lethargy (see also Central nervous system depression in 'Neurological') 2
Vomiting 2
Bloody diarrhoea 2
Lack of efficacy - NOS 1
INEFFECTIVE, ANTIEMETIC 1
Drooling 1
Excitation 1
Low platelet count 1
Seizure NOS 1
Head tremor 1
Cardiac disorder NOS 1
INEFFECTIVE, HEARTWORM LARVAE 1
Elevated alanine aminotransferase (ALT) 1
Leucocytosis NOS 1
Most Referenced Drugs
Milbemycin Oxime + Praziquantel 3
Milbemycin Oxime + Spinosad 2
Spinosad 1
Maropitant Citrate 1
Ivermectin/Pyrantel Pamoate Chewable 272Mcg/652Mg 1
Phenylpropanolamine Hcl 1
Oclacitinib Maleate 1
Selamectin 1
Gentamicin, Mometasone Furoate, And Clotrimazole 1
Prednisone 1
Lotilaner 1
Vaccines (Unknown) 1
Afoxolaner 1
Recombitek Lyme - 2126.R0 1
Grapiprant 1
Outcome Breakdown
Recovered/Normal
4 (33.3%)
Ongoing
3 (25.0%)
Outcome Unknown
3 (25.0%)
Recovered with Sequela
1 (8.3%)
Died
1 (8.3%)
Gender Distribution
Male 6 (54.5%)
Female 5 (45.5%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2012 | 3 | |
| 2013 | 1 | |
| 2015 | 1 | |
| 2016 | 1 | |
| 2018 | 1 | |
| 2019 | 1 | |
| 2020 | 2 | |
| 2022 | 1 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #427 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.