Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
34
Total Reports
2
Deaths Reported
590.0%
Death Rate
4.6 yr
Avg Age at Report
Average weight at time of report: 25.0 kg (55.1 lbs)
Top Reported Reactions
Vomiting 5
Seizure NOS 5
Diarrhoea 5
Lack of efficacy (endoparasite) - heartworm 4
Emesis 3
Lethargy (see also Central nervous system depression in 'Neurological') 3
Lack of efficacy - NOS 3
INEFFECTIVE, HEARTWORM LARVAE 2
Neutrophilia 2
Leucocytosis NOS 2
Ataxia 2
Panting 2
Agitation 2
Lack of efficacy (ectoparasite) - tick NOS 2
Lack of efficacy (bacteria) - Borrelia 2
Most Referenced Drugs
Milbemycin Oxime + Spinosad 11
Milbemycin Oxime + Praziquantel 7
Pyrantel Pamoate;Sarolaner 7
Phenylpropanolamine Hydrochloride 3
Vaccines (Unknown) 2
Sarolaner 2
Famotidine 2
Doxycycline 2
Prednisone 2
Bedinvetmab 2
Lidocaine 2
Tick Treatment (Unknown) 1
Selamectin 1
Spinosad 1
Ivermectin 1
Outcome Breakdown
Recovered/Normal
11 (32.4%)
Outcome Unknown
10 (29.4%)
Ongoing
10 (29.4%)
Died
2 (5.9%)
Recovered with Sequela
1 (2.9%)
Gender Distribution
Female 18 (52.9%)
Male 16 (47.1%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2012 | 2 | |
| 2013 | 2 | |
| 2014 | 1 | |
| 2016 | 1 | |
| 2017 | 3 | |
| 2018 | 2 | |
| 2019 | 2 | |
| 2020 | 2 | |
| 2021 | 5 | |
| 2022 | 4 | |
| 2023 | 1 | |
| 2024 | 5 | |
| 2025 | 4 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #305 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.