Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
19
Total Reports
1
Deaths Reported
530.0%
Death Rate
5.5 yr
Avg Age at Report
Average weight at time of report: 28.0 kg (61.7 lbs)
Top Reported Reactions
Lack of efficacy (endoparasite) - hookworm 5
INEFFECTIVE, HEARTWORM LARVAE 3
Vomiting 3
Pale mucous membrane 2
Lack of efficacy (endoparasite) - heartworm 2
Lack of efficacy - NOS 1
Digestive tract disorder NOS 1
INEFFECTIVE, ASCARIDS NOS 1
Emesis 1
Hair loss NOS 1
Dermatitis 1
Lethargy (see also Central nervous system depression in 'Neurological') 1
Hot spot (pyotraumatic dermatitis) 1
Excessive licking and/or grooming 1
Pacing 1
Most Referenced Drugs
Ivermectin + Pyrantel As Pamoate Salt 5
Milbemycin Oxime + Spinosad 4
Moxidectin 3
Milbemycin Oxime + Praziquantel 3
Lufenuron + Milbemycin Oxime 1
Milbemycin Oxime/Spinosad 1
Ivermectin/Pyrantel Pamoate Chewable 272Mcg/652Mg 1
Phenylpropanolamine Hcl 1
Unknown Steroid 1
Glucosamine, Chondroitin 1
Melarsomine Dihydrochloride Injection 1
Orbiflox/Momet/Posaco Eardrops 1
Canine Influenza Virus H3N8;Canine Influenza Virus H3N2 1
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 1
Milbemycin/Lufenuron/Pzq Chew 1
Outcome Breakdown
Ongoing
7 (36.8%)
Outcome Unknown
7 (36.8%)
Recovered/Normal
3 (15.8%)
Recovered with Sequela
1 (5.3%)
Died
1 (5.3%)
Gender Distribution
Male 10 (52.6%)
Female 9 (47.4%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2012 | 3 | |
| 2013 | 1 | |
| 2014 | 1 | |
| 2017 | 4 | |
| 2018 | 2 | |
| 2020 | 1 | |
| 2021 | 2 | |
| 2022 | 1 | |
| 2023 | 1 | |
| 2024 | 2 | |
| 2025 | 1 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #362 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.