Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
19
Total Reports
2
Deaths Reported
1050.0%
Death Rate
5.3 yr
Avg Age at Report
Average weight at time of report: 19.0 kg (41.9 lbs)
Top Reported Reactions
Vomiting 4
Lack of efficacy (endoparasite) - hookworm 3
Lethargy (see also Central nervous system depression in 'Neurological') 2
Tremor 2
Sterile 1
Emesis 1
Anxiety 1
Depression 1
Elevated liver enzymes 1
Alopecia general 1
Neutrophilia 1
Monocytosis 1
Anorexia 1
Lack of efficacy (flea) 1
Drug dose administration interval too long 1
Most Referenced Drugs
Milbemycin Oxime + Spinosad 4
Milbemycin Oxime + Praziquantel 3
Ivermectin + Pyrantel 2
Fluralaner 2
Lotilaner 2
Spinosad 1
Fluralaner Chew Tablets 1
Rabacfosadine Succinate 1
Desoxycortone 1
Desoxycortone Pivalate 1
Bupivacaine Lipsome Injectable Suspension 1
Flea Product (Unknown) 1
Deracoxib 1
Maropitant Citrate 1
Grapiprant 1
Outcome Breakdown
Outcome Unknown
6 (31.6%)
Ongoing
6 (31.6%)
Recovered/Normal
4 (21.1%)
Recovered with Sequela
1 (5.3%)
Died
1 (5.3%)
Euthanized
1 (5.3%)
Gender Distribution
Male 9 (47.4%)
Female 8 (42.1%)
Unknown 2 (10.5%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2013 | 2 | |
| 2014 | 2 | |
| 2015 | 1 | |
| 2016 | 2 | |
| 2017 | 1 | |
| 2018 | 2 | |
| 2019 | 4 | |
| 2020 | 3 | |
| 2024 | 1 | |
| 2025 | 1 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #366 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.