Drug profile

The FDA adverse-event record for Previcox

99 FDA reports name Previcox, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#782 of 2,679
by report volume (all drugs)
99
adverse-event reports
26.3%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Previcox ranks #777 of 2679 by total reports (99) and #154 of 1130 by death-coded share (26.3%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#777
This drug, reports of 2679
#154
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Previcox has 99 reports now versus 97 in that prior snapshot: 2 more (2.1%).

Report change
+2
Death-coded reports
+1
Death-coded share
+0.5 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Previcox changes

Signature read: Previcox's 26.3% death-coded share is among the highest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
99
Total Reports
26
Deaths Reported
26.3%
Death-coded share of reports

Active Ingredients

Previcox

Administration Routes

OralUnknownSubcutaneous

Species Affected

Dog 98
Horse 1

Most Affected Breeds

Retriever - Labrador 19
Retriever - Golden 10
Boxer (German Boxer) 10
Crossbred Canine/dog 6
Terrier - Bull - American Pit 4
Shepherd Dog - German 4
Spaniel (unspecified) 3
Terrier - Bull - Staffordshire 3
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 3
Collie - Border 2

Most Reported Reactions

Death 16
Ataxia 14
Seizure NOS 11
Lameness 10
Death by euthanasia 9
Not eating 9
Falling 9
Anaemia NOS 9
Leucocytosis NOS 8
Limb weakness 8
Vomiting 8
Lethargy (see also Central nervous system depression in Neurological) 8

Outcome Breakdown

Ongoing
56 (56.6%)
Died
17 (17.2%)
Outcome Unknown
11 (11.1%)
Euthanized
9 (9.1%)
Recovered/Normal
6 (6.1%)

Previcox: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Previcox, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Previcox (#782 of 2,679 by report volume); death-coded 26.3%. PlainBreed drug row · death-coded share stamp 26.3% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →