Drug profile

The FDA adverse-event record for Nystatin, Neomycin Sulfate, Thiostrpton & Traimcinolone

99 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Nystatin, Neomycin Sulfate, Thiostrpton & Traimcinolone. See the species affected, top reactions, and outcomes below.

99
adverse-event reports
16.2%
death-coded share
Dog
most-reported species
30
Lethargy (see also Central nervous system depression in 'Neurological') - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
99
Total Reports
16
Deaths Reported
16.2%
Death Rate

Active Ingredients

Nystatin, Neomycin Sulfate, Thiostrpton & Traimcinolone

Administration Routes

TopicalUnknownAuricular (Otic)Parenteral

Species Affected

Dog 75
Cat 24

Most Affected Breeds

Domestic Shorthair 16
Chihuahua 8
Retriever - Labrador 6
Shih Tzu 5
Domestic Longhair 4
Bulldog - French 4
Terrier - Yorkshire 3
Mixed (Dog) 3
Shepherd Dog - German 3
Retriever - Golden 3

Most Reported Reactions

Lethargy (see also Central nervous system depression in 'Neurological') 30
Vomiting 26
Anorexia 18
Diarrhoea 9
Death by euthanasia 8
Death 7
Other abnormal test result NOS 7
Decreased appetite 6
Elevated alanine aminotransferase (ALT) 6
Elevated liver enzymes 6
Seizure NOS 6
Hives (see also 'Skin') 6

Outcome Breakdown

Ongoing
65 (65.7%)
Recovered/Normal
11 (11.1%)
Died
9 (9.1%)
Outcome Unknown
7 (7.1%)
Euthanized
7 (7.1%)

Nystatin, Neomycin Sulfate, Thiostrpton & Traimcinolone Adverse Event Insights

99 reports name Nystatin, Neomycin Sulfate, Thiostrpton & Traimcinolone; 16 recorded a death outcome (16.2% of reported events, not a population-level mortality rate). Active ingredient: Nystatin, Neomycin Sulfate, Thiostrpton & Traimcinolone. Administration routes: Topical, Unknown, Auricular (Otic), Parenteral.

By species: Dog (75 reports), Cat (24 reports). By breed: Domestic Shorthair (16), Chihuahua (8), Retriever - Labrador (6).

Leading clinical signs: Lethargy (see also Central nervous system depression in 'Neurological') (30), Vomiting (26), Anorexia (18), Diarrhoea (9). Outcome, 99 coded reports: Ongoing leads at 65.7%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.