Amoxicillin + Clavulanic Acid
263 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
263
Total Reports
31
Deaths Reported
1180.0%
Death Rate
Active Ingredients
AmoxicillinAmoxicillin + Clavulanic AcidClavulanic Acid
Administration Routes
UnknownOralAuricular (Otic)
Species Affected
Dog 152
Cat 107
Human 3
Unknown 1
Most Affected Breeds
Domestic Shorthair 73
Retriever - Labrador 15
Cat (unknown) 10
Shih Tzu 9
Domestic Longhair 9
Retriever - Golden 6
Spitz - German Pomeranian 6
Bulldog - French 6
Unknown 5
Pointing Dog - Hungarian Short-haired (Vizsla) 5
Most Reported Reactions
Vomiting 51
Lethargy (see also Central nervous system depression in Neurological) 39
Other abnormal test result NOS 38
Decreased appetite 36
Not eating 32
Diarrhoea 27
Weight loss 27
Death by euthanasia 26
Elevated alanine aminotransferase (ALT) 24
Behavioural disorder NOS 24
Leucocytosis NOS 23
Hyperglycaemia 23
Outcome Breakdown
Ongoing
99 (37.6%)
Outcome Unknown
87 (33.1%)
Recovered/Normal
45 (17.1%)
Euthanized
25 (9.5%)
Died
6 (2.3%)
Recovered with Sequela
1 (0.4%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.