Total Reports
14
Low report volume
Dog /
Breed profile · FDA CVM July 2026 extract
Karelian Bear Dog adverse-event record
Adverse-event filings for Karelian Bear Dog (Dog) in the FDA Center for Veterinary Medicine openFDA extract. Browse dog breeds, reactions, and outcomes below.
- #407 of 510
- by report volume (all breeds)
- 14
- FDA CVM reports on file
- 7.1%
- death-coded share of reports
- 4
- Lethargy (see also Central nervous system depression in 'Neurological') - top reaction
How the 14 reports break down
By recorded gender -- every report on file for Karelian Bear Dog, no filtering.
Annual report volume
Data updated September 2026
The verdict
According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Karelian Bear Dog ranks #404 of 510 by total reports (14). Death-coded-share rank requires at least 50 reports. National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).
- 93,675
- Retriever - Labrador reports (#1)
- 99.0%
- Atlantic Salmon (Salmo salar) death share (#1)
- #404
- This breed, reports of 510
Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.
Release-over-release change
What changed in the latest FDA data snapshot
PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Karelian Bear Dog has 14 reports now versus 14 in that prior snapshot: 0 the same number of (0.0%).
- Report change
- +0
- Death-coded reports
- +0
- Death-coded share
- −0.0 pts
This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.
Subscribe to Karelian Bear Dog changesDeaths Reported
1
of 14 reports
Death-coded share of reports
7.1%
7.1% death-coded
Avg Age at Report
7.0 yr
27.0 kg avg weight
Death-Coded Outcome Share
Karelian Bear Dog death-coded reports 7.1%
Cross-breed median
7.1% of 14 karelian bear dog reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 27.0 kg (59.5 lbs)
Top Reported Reactions
Lethargy (see also Central nervous system depression in 'Neurological') 4
Emesis 2
Seizure NOS 2
Weight loss 1
Lack of efficacy - NOS 1
Most Referenced Drugs
Milbemycin Oxime + Spinosad 4
Afoxolaner 2
Ivermectin + Pyrantel As Pamoate Salt 2
Milbemycin Oxime + Praziquantel 2
Prednisolone Trimeprazine Tartrate 1
Outcome Breakdown
Outcome Unknown
5 (35.7%)
Recovered/Normal
4 (28.6%)
Ongoing
4 (28.6%)
Euthanized
1 (7.1%)
Gender Distribution
Male 8 (57.1%)
Female 5 (35.7%)
Unknown 1 (7.1%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2012 | 1 | |
| 2013 | 1 | |
| 2014 | 2 | |
| 2016 | 2 | |
| 2017 | 2 | |
| 2019 | 2 | |
| 2022 | 1 | |
| 2023 | 2 | |
| 2025 | 1 | |
Karelian Bear Dog: high death-coded share in the FDA CVM extract
Signature read: 14 reports place Karelian Bear Dog in the lower third of breed filing volume (#407 of 510). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Karelian Bear Dog sits at #407 of 510 by report volume among all breeds and #262 of 298 among dog breeds, with 14 reports and 1 (7.1%) death-coded. Mean age at report: 7.0 years, average weight 27.0 kg (59.5 lbs).
Top reported signs: Lethargy (see also Central nervous system depression in 'Neurological') (4), Emesis (2), Seizure NOS (2). Most-referenced drug: Milbemycin Oxime + Spinosad (4 reports), followed by Afoxolaner (2) and Ivermectin + Pyrantel As Pamoate Salt (2).
Outcome coding on 14 status-recorded reports is dominated by Outcome Unknown (35.7%). Annual submissions ranged 1-2,025 across 9 years on file.
Dog Breeds With a Similar Report Volume
Showing 6 of 297 dog breeds in our dataset, ranked by closest report volume.
Canaan Dog
14 reports · 7.1% death-coded
Hound - Swiss - (Lucerne Hound (Luzerner Laufhund), Schwyz Hound (Schweizer Laufhund), Bernese Hound, Jura Hound)
14 reports · 0.0% death-coded
Munsterlander - Large
14 reports · 0.0% death-coded
Hovawart
13 reports · 0.0% death-coded
Ridgeback (unspecified)
13 reports · 0.0% death-coded
Spaniel - Portuguese Water
15 reports · 0.0% death-coded
Nationwide breeds with similar profiles
Sparse-volume peer sets for Karelian Bear Dog drawn from openFDA outside the Dog family so the neighborhoods are not species containment (the similar-volume list above stays within species).
Similar average weight
Nearest other-species breeds by reported average weight (27.0 kg here).
What to do with this dog
- Compare Karelian Bear Dog's report volume and death-coded share against similar-volume breeds nationwide. See similar breeds
- Read how death-coded share differs from a mortality rate before drawing conclusions. Breed-specific risks guide
- Browse every dog breed we track for comparison. All dog breeds
A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.
Frequently Asked Questions
How many FDA adverse event reports involve Karelian Bear Dog? ▼
There are 14 adverse event reports involving Karelian Bear Dog in the FDA database, of which 1 were death-coded (7.1% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Karelian Bear Dog ranks #407 of 510 by report volume among all breeds PlainBreed indexes (#262 of 298 among dog breeds).
Where does Karelian Bear Dog sit among other breeds in PlainBreed's corpus? ▼
According to FDA CVM report volume, Karelian Bear Dog is #407 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Dog, it is #262 of 298. It has fewer than 50 reports, so it is outside the death-rate ranking cohort (≥50 reports). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Karelian Bear Dog? ▼
The most commonly reported adverse reactions for Karelian Bear Dog are Lethargy (see also Central nervous system depression in 'Neurological') (4 reports), Emesis (2 reports), Seizure NOS (2 reports), Weight loss (1 reports), Lack of efficacy - NOS (1 reports).
What drugs are most frequently associated with Karelian Bear Dog adverse events? ▼
The drugs most frequently referenced in Karelian Bear Dog adverse event reports are Milbemycin Oxime + Spinosad (4 reports), Afoxolaner (2 reports), Ivermectin + Pyrantel As Pamoate Salt (2 reports), Milbemycin Oxime + Praziquantel (2 reports), Prednisolone Trimeprazine Tartrate (1 reports).
What is the average age of Karelian Bear Dog in adverse event reports? ▼
The average age of Karelian Bear Dog at the time of adverse event reports is 7.0 years, with an average weight of 27.0 kg (59.5 lbs).
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how the death-coded share and rankings are computed, or read breed-specific reporting patterns and FDA CVM reporting.
Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025
openFDA Animal & Veterinary Adverse Events (FDA CVM) for Karelian Bear Dog (Dog), extract as of July 2026 extract. 14 reports · 1 death-coded (7.1% of reports, not a mortality rate) · #407 of 510 by volume.
Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →