Total Reports
14
FDA CVM filings
Dog /
FDA CVM · 2025 release 14 reports on file
Karelian Bear Dog - FDA Adverse Event Profile
Adverse-event records for Karelian Bear Dog (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
Karelian Bear Dog's FDA record: #401 most-reported dog breed, 14 total reports, 7.1% death-coded (1 reports).
- #401
- most-reported dog breed
- 7.1%
- death-coded report share
- 4
- Lethargy (see also Central nervous system depression in 'Neurological') - top reaction
- 7.0 yr
- average age at report
Report counts track breed popularity and reporting activity, not real-world risk, read this alongside how common the breed is.
Deaths Reported
1
of 14 reports
Death Rate
7.1%
death-coded share
Avg Age at Report
7.0 yr
27.0 kg avg weight
Death-Coded Outcome Share
Karelian Bear Dog death-coded reports 7.1%
Cross-breed median
7.1% of 14 karelian bear dog reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 27.0 kg (59.5 lbs)
Top Reported Reactions
Lethargy (see also Central nervous system depression in 'Neurological') 4
Emesis 2
Seizure NOS 2
Weight loss 1
Lack of efficacy - NOS 1
Most Referenced Drugs
Milbemycin Oxime + Spinosad 4
Afoxolaner 2
Ivermectin + Pyrantel As Pamoate Salt 2
Milbemycin Oxime + Praziquantel 2
Prednisolone Trimeprazine Tartrate 1
Outcome Breakdown
Outcome Unknown
5 (35.7%)
Recovered/Normal
4 (28.6%)
Ongoing
4 (28.6%)
Euthanized
1 (7.1%)
Gender Distribution
Male 8 (57.1%)
Female 5 (35.7%)
Unknown 1 (7.1%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2012 | 1 | |
| 2013 | 1 | |
| 2014 | 2 | |
| 2016 | 2 | |
| 2017 | 2 | |
| 2019 | 2 | |
| 2022 | 1 | |
| 2023 | 2 | |
| 2025 | 1 | |
Karelian Bear Dog Pet Health Insights
Karelian Bear Dog accounts for 14 FDA adverse event reports, ranking #401 by volume among dog breeds, with 1 reports (7.1%) coded as a death outcome. Mean age at report: 7.0 years, average weight 27.0 kg (59.5 lbs).
Top reported signs: Lethargy (see also Central nervous system depression in 'Neurological') (4), Emesis (2), Seizure NOS (2). Most-referenced drug: Milbemycin Oxime + Spinosad (4 reports), followed by Afoxolaner (2) and Ivermectin + Pyrantel As Pamoate Salt (2).
Outcome coding on 14 status-recorded reports is dominated by Outcome Unknown (35.7%). Annual submissions ranged 2,012-2,025 across 9 years on file.
Dog Breeds With a Similar Report Volume
Hound - Swiss - (Lucerne Hound (Luzerner Laufhund), Schwyz Hound (Schweizer Laufhund), Bernese Hound, Jura Hound)
14 reports · 0.0% death rate
Canaan Dog
13 reports · 7.7% death rate
Hovawart
13 reports · 0.0% death rate
Munsterlander - Large
13 reports · 0.0% death rate
Pointing Dog - Hungarian Wire-haired (Vizsla)
15 reports · 0.0% death rate
Spaniel - Portuguese Water
13 reports · 0.0% death rate
Frequently Asked Questions
How many FDA adverse event reports involve Karelian Bear Dog? ▼
There are 14 adverse event reports involving Karelian Bear Dog in the FDA database, with 1 reports involving death (7.1% death rate). Karelian Bear Dog ranks #401 by report volume.
What are the most common adverse reactions reported for Karelian Bear Dog? ▼
The most commonly reported adverse reactions for Karelian Bear Dog are Lethargy (see also Central nervous system depression in 'Neurological') (4 reports), Emesis (2 reports), Seizure NOS (2 reports), Weight loss (1 reports), Lack of efficacy - NOS (1 reports).
What drugs are most frequently associated with Karelian Bear Dog adverse events? ▼
The drugs most frequently referenced in Karelian Bear Dog adverse event reports are Milbemycin Oxime + Spinosad (4 reports), Afoxolaner (2 reports), Ivermectin + Pyrantel As Pamoate Salt (2 reports), Milbemycin Oxime + Praziquantel (2 reports), Prednisolone Trimeprazine Tartrate (1 reports).
What is the average age of Karelian Bear Dog in adverse event reports? ▼
The average age of Karelian Bear Dog at the time of adverse event reports is 7.0 years, with an average weight of 27.0 kg (59.5 lbs).
Does a high number of adverse event reports mean Karelian Bear Dog is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Karelian Bear Dog safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.