Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
14
Total Reports
1
Deaths Reported
710.0%
Death Rate
7.0 yr
Avg Age at Report
Average weight at time of report: 27.0 kg (59.5 lbs)
Top Reported Reactions
Lethargy (see also Central nervous system depression in 'Neurological') 4
Emesis 2
Seizure NOS 2
Weight loss 1
Lack of efficacy - NOS 1
INEFFECTIVE, ASCARIDS NOS 1
Elevated serum alkaline phosphatase (SAP) 1
Not eating 1
Constipation 1
Skin disorders NOS 1
Generalised rash 1
Foaming at the mouth 1
Inappropriate defecation 1
Transient blindness 1
Confused 1
Most Referenced Drugs
Milbemycin Oxime + Spinosad 4
Afoxolaner 2
Ivermectin + Pyrantel As Pamoate Salt 2
Milbemycin Oxime + Praziquantel 2
Prednisolone Trimeprazine Tartrate 1
Bordetella Vaccine 1
Rabies Vaccine 1
Da2Pp Vaccine 1
Carprofen 1
Fluralaner Chew Tablets 1
Ivermectin 1
Oclacitinib Maleate 1
Borrelia Burgdorferi Bacterin 1
Sarolaner 1
Bedinvetmab 1
Outcome Breakdown
Outcome Unknown
5 (35.7%)
Recovered/Normal
4 (28.6%)
Ongoing
4 (28.6%)
Euthanized
1 (7.1%)
Gender Distribution
Male 8 (57.1%)
Female 5 (35.7%)
Unknown 1 (7.1%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2012 | 1 | |
| 2013 | 1 | |
| 2014 | 2 | |
| 2016 | 2 | |
| 2017 | 2 | |
| 2019 | 2 | |
| 2022 | 1 | |
| 2023 | 2 | |
| 2025 | 1 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #401 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.