Frog

Frog Adverse Event Insights

The FDA Center for Veterinary Medicine database holds 11 adverse event reports for Frog, distributed across 2 distinct breeds currently tracked in the system. Of those reports, 2 involved a death outcome — producing a 1820.0% case-fatality rate among reported events, which reflects reporting severity bias rather than true population mortality. These figures are aggregated directly from openFDA's Animal & Veterinary Adverse Events endpoint and update as new voluntary submissions flow through pet owners, veterinarians, and drug manufacturers.

The most frequently reported clinical signs for Frog are Lack of efficacy - NOS (4 reports), INEFFECTIVE, OVULATION (3 reports), Necropsy performed (2 reports), Digestive tract disorder NOS (1 reports), with Lack of efficacy - NOS leading the reaction traffic at 4 submissions. On the product side, Hcg (Fd) Injectable is the single most-referenced drug with 6 reports, followed by Flunixin Megl Topical Solution (2), Dexmedetomidine Hydrochloride (1), Atipamezole Hydrochloride (1). This combination surfaces which therapeutic classes generate the most adverse event chatter for this species — a useful starting point when comparing Frog reporting patterns against other companion animals in the dataset.

Of the 11 Frog reports with a coded outcome, Outcome Unknown accounts for the largest share at 54.5%. Annual submission volume spans 2,011 to 2,023 reports across the 8 years on file, a range that reflects evolving owner awareness, veterinary reporting habits, and new product approvals rather than stable underlying incidence. The breed-level table below breaks these patterns down further, showing how the 2 tracked frog breeds compare on volume, deaths, and average age at report. As with all FDA adverse event data, correlation is the ceiling — causation requires clinical investigation beyond what these aggregates can provide.