Species profile · FDA CVM July 2026 extract

Buffalo adverse-event record

According to FDA CVM openFDA filings as of July 2026 extract, 9 adverse-event reports span 0 buffalo breeds.

#42 of 55
by report volume (all species)
9
adverse-event reports
0
breeds in this species
77.8%
death-coded share

The record at a glance

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Buffalo ranks #42 of 55 by total reports (9) and #0 of 41 by death-coded share (77.8%). National dual: Dog is #1 of 55 species by total adverse-event reports (806,331) at death-coded share 4.3% (rank 38 of 41); separately, Quail is #1 highest death-coded share at 84.6% (report rank #32).

806,331
Dog reports (#1)
84.6%
Quail death share (#1)
#42
This species, reports of 55
#0
This species, death share of 41

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Buffalo has 9 reports now versus 9 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Buffalo changes
9
Total Reports
0
Breeds
7
Deaths
77.8%
Death Rate

Top Reactions

Death 4
Unexplained death 2
Drug administration error 2
INEFFECTIVE, WORMS NOS 2
Anorexia 1
PR-LIVER, LESION(S) 1
PR-LUNG(S), LESION(S) 1
Lack of efficacy (bacteria) - NOS 1
Lack of efficacy (protozoa) - Coccidia 1
Lack of efficacy (endoparasite) - tapeworm 1
Lack of efficacy (endoparasite) - roundworm NOS 1
INEFFECTIVE, STOMACH WORM NOS 1

Most Referenced Drugs

Doramectin 2
Albendazole 2
Tylosin 1
Oxytetracycline 1
Fenbendazole 1
Tiletamine + Zolazepam 1
Doramectin; Phenol 1

Outcome Breakdown

Died
7 (87.5%)
Outcome Unknown
1 (12.5%)

Reports by Year

2010
1
2011
2
2012
1
2013
1
2016
1
2017
1
2018
2

Buffalo Adverse Event Insights

The FDA Center for Veterinary Medicine database holds 9 adverse event reports for Buffalo, distributed across 0 distinct breeds currently tracked in the system. Of those reports, 7 involved a death outcome, producing a 77.8% case-fatality rate among reported events, which reflects reporting severity bias rather than true population mortality. These figures are aggregated directly from openFDA's Animal & Veterinary Adverse Events endpoint and update as new voluntary submissions flow through pet owners, veterinarians, and drug manufacturers.

The most frequently reported clinical signs for Buffalo are Death (4 reports), Unexplained death (2 reports), Drug administration error (2 reports), INEFFECTIVE, WORMS NOS (2 reports), with Death leading the reaction traffic at 4 submissions. On the product side, Doramectin is the single most-referenced drug with 2 reports, followed by Albendazole (2), Tylosin (1), Oxytetracycline (1). This combination surfaces which therapeutic classes generate the most adverse event chatter for this species, a useful starting point when comparing Buffalo reporting patterns against other companion animals in the dataset.

Of the 8 Buffalo reports with a coded outcome, Died accounts for the largest share at 87.5%. Annual submission volume spans 1 to 2 reports across the 7 years on file, a range that reflects evolving owner awareness, veterinary reporting habits, and new product approvals rather than stable underlying incidence. The breed-level table below breaks these patterns down further, showing how the 0 tracked buffalo breeds compare on volume, deaths, and average age at report. As with all FDA adverse event data, correlation is the ceiling, causation requires clinical investigation beyond what these aggregates can provide.

Buffalo Breeds (0)

# Breed Reports Deaths Death Rate Avg Age

What to do with buffalo data

  • Look up any buffalo breed's report volume and death-coded share in the full breed directory. Browse breeds
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Breed-specific risks guide
  • See how species compare nationwide by report volume and death-coded share. Rankings

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Data sourced from the FDA Center for Veterinary Medicine (openFDA Animal & Veterinary Adverse Events). See our methodology for details. Retrieved and formatted by PlainBreed.

According to the FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Event extract, every figure on this page is rendered from that public file; no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.