Drug profile

The FDA adverse-event record for Zymox

11 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Zymox. See the species affected, top reactions, and outcomes below.

11
adverse-event reports
45.5%
death-coded share
Dog
most-reported species
5
Death by euthanasia - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
11
Total Reports
5
Deaths Reported
45.5%
Death Rate

Active Ingredients

Zymox

Administration Routes

UnknownAuricular (Otic)Topical

Species Affected

Dog 8
Cat 3

Most Affected Breeds

Domestic Shorthair 3
Dachshund - Standard Smooth-haired 1
Shepherd Dog - German 1
Pug 1
Bulldog - American 1
Retriever - Labrador 1
Shih Tzu 1
Crossbred Canine/dog 1
Poodle - Miniature 1

Most Reported Reactions

Death by euthanasia 5
Not himself/herself 3
Diarrhoea 2
Elevated serum alkaline phosphatase (SAP) 2
Elevated globulins 2
Increased salivation 2
Dyspnoea 2
Abnormal radiograph finding 2
Thrombocytosis 2
Elevated blood urea nitrogen (BUN) 2
Elevated creatinine 2
Hind limb paralysis 2

Outcome Breakdown

Euthanized
5 (45.5%)
Ongoing
3 (27.3%)
Outcome Unknown
2 (18.2%)
Recovered/Normal
1 (9.1%)

Zymox Adverse Event Insights

11 reports name Zymox; 5 recorded a death outcome (45.5% of reported events, not a population-level mortality rate). Active ingredient: Zymox. Administration routes: Unknown, Auricular (Otic), Topical.

By species: Dog (8 reports), Cat (3 reports). By breed: Domestic Shorthair (3), Dachshund - Standard Smooth-haired (1), Shepherd Dog - German (1).

Leading clinical signs: Death by euthanasia (5), Not himself/herself (3), Diarrhoea (2), Elevated serum alkaline phosphatase (SAP) (2). Outcome, 11 coded reports: Euthanized leads at 45.5%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.