Drug profile

The FDA adverse-event record for Unspecified Flea Spray

Name: Unspecified Flea Spray - FDA Animal Adverse Event Reports
Creator: PlainBreed
License: https://creativecommons.org/publicdomain/zero/1.0/

14 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Unspecified Flea Spray. See the species affected, top reactions, and outcomes below.

14
adverse-event reports: 14.3%
death-coded share: Dog
most-reported species: 10
Lack of efficacy (ectoparasite) - flea - top reaction

Compiled by PlainBreed Editorial, Pet Health Editorial Team

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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

Total Reports

Deaths Reported

14.3%

Death Rate

Active Ingredients

Unspecified Flea Spray

Administration Routes

TopicalUnknownOralOther

Species Affected

Dog 11

Cat 3

Most Affected Breeds

Shepherd Dog - Australian 3

Domestic Shorthair 2

Spitz - German Pomeranian 1

Maltese 1

Retriever - Golden 1

Weimaraner 1

Siberian Husky 1

Cat (unknown) 1

Boxer (German Boxer) 1

Pit Bull 1

Most Reported Reactions

Lack of efficacy (ectoparasite) - flea 10

Death 2

Vomiting 1

Papule 1

Pruritus 1

Skin sore 1

Drug dose administration interval too short 1

Itching 1

Reddening of the skin 1

Rash 1

Scratching 1

Coma 1

Outcome Breakdown

Outcome Unknown

12 (85.7%)

Died

2 (14.3%)

Unspecified Flea Spray Adverse Event Insights

14 reports name Unspecified Flea Spray; 2 recorded a death outcome (14.3% of reported events, not a population-level mortality rate). Active ingredient: Unspecified Flea Spray. Administration routes: Topical, Unknown, Oral, Other.

By species: Dog (11 reports), Cat (3 reports). By breed: Shepherd Dog - Australian (3), Domestic Shorthair (2), Spitz - German Pomeranian (1).

Leading clinical signs: Lack of efficacy (ectoparasite) - flea (10), Death (2), Vomiting (1), Papule (1). Outcome, 14 coded reports: Outcome Unknown leads at 85.7%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.