Drug profile

The FDA adverse-event record for Unknown Leptospirosis Vaccine

11 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Unknown Leptospirosis Vaccine. See the species affected, top reactions, and outcomes below.

11
adverse-event reports
18.2%
death-coded share
Dog
most-reported species
3
Urinary tract infection - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
11
Total Reports
2
Deaths Reported
18.2%
Death Rate

Active Ingredients

Unknown Leptospirosis Vaccine

Administration Routes

UnknownOtherSubcutaneous

Species Affected

Dog 11

Most Affected Breeds

Retriever - Labrador 3
Beagle 1
Shih Tzu 1
Mastiff (unspecified) 1
Terrier - Bull - American Pit 1
Retriever - Golden 1
Shepherd Dog - German 1
Shiba Inu 1
Coonhound - Black and Tan 1

Most Reported Reactions

Urinary tract infection 3
Elevated liver enzymes 2
Appetite loss 2
Elevated total bilirubin 2
Ascites 2
Renal failure 2
Liver disorder NOS 2
Discoloured urine 2
Constipation 2
Hair shedding 2
Death by euthanasia 2
Liver failure 2

Outcome Breakdown

Outcome Unknown
4 (36.4%)
Ongoing
4 (36.4%)
Euthanized
2 (18.2%)
Recovered/Normal
1 (9.1%)

Unknown Leptospirosis Vaccine Adverse Event Insights

11 reports name Unknown Leptospirosis Vaccine; 2 recorded a death outcome (18.2% of reported events, not a population-level mortality rate). Active ingredient: Unknown Leptospirosis Vaccine. Administration routes: Unknown, Other, Subcutaneous.

By species: Dog (11 reports). By breed: Retriever - Labrador (3), Beagle (1), Shih Tzu (1).

Leading clinical signs: Urinary tract infection (3), Elevated liver enzymes (2), Appetite loss (2), Elevated total bilirubin (2). Outcome, 11 coded reports: Outcome Unknown leads at 36.4%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.