Drug profile

The FDA adverse-event record for Triple Antibiotic Ointment

18 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Triple Antibiotic Ointment. See the species affected, top reactions, and outcomes below.

18
adverse-event reports
5.6%
death-coded share
Dog
most-reported species
4
Pruritus - top reaction
Verify with FDA CVM →
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
18
Total Reports
1
Deaths Reported
5.6%
Death Rate

Active Ingredients

Triple Antibiotic Ointment

Administration Routes

TopicalUnknownOphthalmicAuricular (Otic)

Species Affected

Dog 11
Cat 5
Horse 2

Most Affected Breeds

Domestic Shorthair 3
Maine Coon 2
Shih Tzu 2
Retriever - Labrador 2
Paint 1
Schnauzer - Miniature 1
Maltese 1
Boxer (German Boxer) 1
Dachshund - Miniature 1
Chihuahua 1

Most Reported Reactions

Pruritus 4
Lethargy (see also Central nervous system depression in 'Neurological') 4
Application site alopecia 3
Application site scab 3
Elevated creatinine 3
Blepharospasm 2
Alopecia NOS 2
Crust 2
Diarrhoea 2
Other abnormal test result NOS 2
Keratoconjunctivitis sicca 2
Anorexia 2

Outcome Breakdown

Recovered/Normal
8 (44.4%)
Outcome Unknown
8 (44.4%)
Ongoing
1 (5.6%)
Died
1 (5.6%)

Triple Antibiotic Ointment Adverse Event Insights

18 reports name Triple Antibiotic Ointment; 1 recorded a death outcome (5.6% of reported events, not a population-level mortality rate). Active ingredient: Triple Antibiotic Ointment. Administration routes: Topical, Unknown, Ophthalmic, Auricular (Otic).

By species: Dog (11 reports), Cat (5 reports), Horse (2 reports). By breed: Domestic Shorthair (3), Maine Coon (2), Shih Tzu (2).

Leading clinical signs: Pruritus (4), Lethargy (see also Central nervous system depression in 'Neurological') (4), Application site alopecia (3), Application site scab (3). Outcome, 18 coded reports: Recovered/Normal leads at 44.4%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.