Drug profile

The FDA adverse-event record for Trimeprazine With Prednisolone

32 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Trimeprazine With Prednisolone. See the species affected, top reactions, and outcomes below.

32
adverse-event reports
3.1%
death-coded share
Dog
most-reported species
6
Other abnormal test result NOS - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
32
Total Reports
1
Deaths Reported
3.1%
Death Rate

Active Ingredients

Trimeprazine With Prednisolone

Administration Routes

OralUnknown

Species Affected

Dog 32

Most Affected Breeds

Retriever - Golden 4
Shih Tzu 3
Terrier - Jack Russell 3
Crossbred Canine/dog 3
Spitz - German Pomeranian 2
Terrier - Boston 2
Spaniel - Cocker American 2
Bichon Frise 2
Beagle 1
Pit Bull 1

Most Reported Reactions

Other abnormal test result NOS 6
Vomiting 4
Lethargy (see also Central nervous system depression in 'Neurological') 4
Pruritus 3
Emesis 3
Weight gain 2
Hyperpigmentation 2
Decreased appetite 2
INEFFECTIVE, ATOPY CONTROL 2
Elevated serum alkaline phosphatase (SAP) 2
Elevated alanine aminotransferase (ALT) 2
Skin hyperaemia 1

Outcome Breakdown

Recovered/Normal
16 (50.0%)
Outcome Unknown
10 (31.3%)
Ongoing
5 (15.6%)
Euthanized
1 (3.1%)

Trimeprazine With Prednisolone Adverse Event Insights

32 reports name Trimeprazine With Prednisolone; 1 recorded a death outcome (3.1% of reported events, not a population-level mortality rate). Active ingredient: Trimeprazine With Prednisolone. Administration routes: Oral, Unknown.

By species: Dog (32 reports). By breed: Retriever - Golden (4), Shih Tzu (3), Terrier - Jack Russell (3).

Leading clinical signs: Other abnormal test result NOS (6), Vomiting (4), Lethargy (see also Central nervous system depression in 'Neurological') (4), Pruritus (3). Outcome, 32 coded reports: Recovered/Normal leads at 50.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.